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Isoxazolidines as Ripk1 Inhibitors Patent Publication

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Published March 18th, 2026
Detected March 25th, 2026
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Summary

The European Patent Office has published patent application EP4709716A1 concerning isoxazolidines as Ripk1 inhibitors. The publication lists Genzyme Corporation as the applicant and details various inventors and IPC classifications related to pharmaceutical compounds and their therapeutic uses.

What changed

The European Patent Office (EPO) has published patent application EP4709716A1, titled 'Isoxazolidines as Ripk1 Inhibitors and Use Thereof.' The application, filed by Genzyme Corporation, details specific chemical compounds (isoxazolidines) and their potential use as inhibitors of Ripk1, a protein kinase implicated in various inflammatory and cell death pathways. The publication includes detailed International Patent Classification (IPC) codes related to organic chemistry, medicinal preparations, and therapeutic uses, particularly for neurodegenerative conditions (A61P 25/28).

This patent publication is primarily an informational notice regarding intellectual property. It does not impose new regulatory obligations or compliance deadlines on pharmaceutical companies or drug manufacturers. However, it is relevant for entities operating in the pharmaceutical research and development sector, particularly those involved in inflammatory disease research, as it may indicate a new area of patent protection and potential market competition. Companies should note this publication for competitive intelligence and intellectual property landscape monitoring.

Source document (simplified)

← EPO Patent Bulletin

ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF

Publication EP4709716A1 Kind: A1 Mar 18, 2026

Applicants

GENZYME CORPORATION

Inventors

DEFOSSA, Elisabeth, GRIESANG, Niels, HEINELT, Uwe, MATTER, Hans, MENDEZ-PEREZ, Maria, RACKELMANN, Nils, SCHWINK, Lothar

IPC Classifications

C07D 261/02 20060101AFI20241115BHEP C07D 413/12 20060101ALI20241115BHEP C07D 413/14 20060101ALI20241115BHEP C07D 487/04 20060101ALI20241115BHEP A61P 25/28 20060101ALI20241115BHEP A61K 31/41 20060101ALI20241115BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

Isoxazolidines as Ripk1 Inhibitors and Use Thereof

Classification

Agency
EPO
Published
March 18th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP4709716A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Patent Filing
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Intellectual Property Drug Development

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