Changeflow GovPing Pharma & Drug Safety Isoxazolidines as RIPK1 Inhibitors for Therapeu...
Routine Notice Added Final

Isoxazolidines as RIPK1 Inhibitors for Therapeutic Use

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Published March 18th, 2026
Detected March 25th, 2026
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Summary

The European Patent Office has published patent application EP4709722A1 concerning isoxazolidines as RIPK1 inhibitors for therapeutic use, filed by Genzyme Corporation. This publication details potential new therapeutic agents and their applications.

What changed

The European Patent Office (EPO) has published patent application EP4709722A1, filed by Genzyme Corporation, detailing the use of isoxazolidines as RIPK1 inhibitors for therapeutic applications. The publication includes specific chemical classifications (IPC) and lists designated states within the European Patent Convention where protection is sought. This is a standard patent publication and does not impose new regulatory obligations.

This patent application is primarily of interest to pharmaceutical and biotechnology companies involved in drug discovery and development, particularly in areas related to inflammation and neurodegenerative diseases where RIPK1 inhibitors may be relevant. Compliance officers should note this as a potential development in the intellectual property landscape for therapeutic agents, but no immediate compliance actions are required by regulated entities.

Source document (simplified)

← EPO Patent Bulletin

ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF

Publication EP4709722A1 Kind: A1 Mar 18, 2026

Applicants

GENZYME CORPORATION

Inventors

DEFOSSA, Elisabeth, GRIESANG, Niels, HEINELT, Uwe, MATTER, Hans, MENDEZ-PEREZ, Maria, RACKELMANN, Nils, SCHWINK, Lothar

IPC Classifications

C07D 413/02 20060101AFI20241115BHEP C07D 413/14 20060101ALI20241115BHEP C07D 471/00 20060101ALI20241115BHEP A61P 25/28 20060101ALI20241115BHEP A61K 31/41 20060101ALI20241115BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF

Classification

Agency
EPO
Published
March 18th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP4709722A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Drug Development Intellectual Property

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