Changeflow GovPing Pharma & Drug Safety EPO Patent: Isoxazolidines as Ripk1 Inhibitors
Routine Notice Added Final

EPO Patent: Isoxazolidines as Ripk1 Inhibitors

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Published March 18th, 2026
Detected March 25th, 2026
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Summary

The European Patent Office has published patent application EP4709723A1 concerning isoxazolidines as Ripk1 inhibitors for therapeutic use, filed by Genzyme Corporation. This publication details a new potential therapeutic compound and its application.

What changed

The European Patent Office (EPO) has published patent application EP4709723A1, detailing the invention of isoxazolidines as inhibitors of Ripk1 for therapeutic applications. The applicant is Genzyme Corporation, and the publication date is March 18, 2026. This patent application covers the chemical structure of the compounds and their use in treating conditions where Ripk1 inhibition is beneficial.

This publication represents a new intellectual property filing and does not impose immediate compliance obligations on regulated entities. However, it is relevant for pharmaceutical and drug manufacturers monitoring the patent landscape for new therapeutic agents. Companies involved in Ripk1 inhibitor research or development should review this patent to assess potential overlaps or licensing opportunities.

Source document (simplified)

← EPO Patent Bulletin

ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF

Publication EP4709723A1 Kind: A1 Mar 18, 2026

Applicants

GENZYME CORPORATION

Inventors

DEFOSSA, Elisabeth, RACKELMANN, Nils, HEINELT, Uwe, MATTER, Hans, MENDEZ-PEREZ, Maria, RITTER, Kurt, SZILLAT, Hauke, ZECH, Gernot

IPC Classifications

C07D 413/14 20060101AFI20241115BHEP A61P 25/28 20060101ALI20241115BHEP A61K 31/495 20060101ALI20241115BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF

Classification

Agency
EPO
Published
March 18th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP4709723A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Patent Filing
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Intellectual Property Drug Development

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