EPO Patent: Isoxazolidines as Ripk1 Inhibitors
Summary
The European Patent Office has published patent application EP4709723A1 concerning isoxazolidines as Ripk1 inhibitors for therapeutic use, filed by Genzyme Corporation. This publication details a new potential therapeutic compound and its application.
What changed
The European Patent Office (EPO) has published patent application EP4709723A1, detailing the invention of isoxazolidines as inhibitors of Ripk1 for therapeutic applications. The applicant is Genzyme Corporation, and the publication date is March 18, 2026. This patent application covers the chemical structure of the compounds and their use in treating conditions where Ripk1 inhibition is beneficial.
This publication represents a new intellectual property filing and does not impose immediate compliance obligations on regulated entities. However, it is relevant for pharmaceutical and drug manufacturers monitoring the patent landscape for new therapeutic agents. Companies involved in Ripk1 inhibitor research or development should review this patent to assess potential overlaps or licensing opportunities.
Source document (simplified)
ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF
Publication EP4709723A1 Kind: A1 Mar 18, 2026
Applicants
GENZYME CORPORATION
Inventors
DEFOSSA, Elisabeth, RACKELMANN, Nils, HEINELT, Uwe, MATTER, Hans, MENDEZ-PEREZ, Maria, RITTER, Kurt, SZILLAT, Hauke, ZECH, Gernot
IPC Classifications
C07D 413/14 20060101AFI20241115BHEP A61P 25/28 20060101ALI20241115BHEP A61K 31/495 20060101ALI20241115BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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