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Intestinal Crypt Arrays with Stem Cell and Differentiated Cell Zones - Patent

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office published patent application EP3802848A1 for the University of North Carolina at Chapel Hill, covering methods for forming arrays of planar intestinal crypts possessing a stem/proliferative cell compartment and differentiated cell zone. The patent names inventors Albritton, Wang, and Kim, with IPC classifications in C12Q, C12N, A61L, and A61K. Designated states include all EU contracting states.

What changed

EPO published patent application EP3802848A1 titled 'Formation of arrays of planar intestinal crypts possessing a stem/proliferative cell compartment and differentiated cell zone' for the University of North Carolina at Chapel Hill. The invention covers methods for creating in vitro intestinal crypt arrays with defined cellular compartments, with inventors including Albritton, Wang, and Kim. The patent application is classified under multiple IPC codes including C12Q 1/08, C12N 5/071, and A61L 27/00, covering biological testing methods, cell cultures, and implant materials.

Patent holders should monitor for the patent grant decision, file national phase applications in desired jurisdictions (US, Japan, China, Korea), and conduct freedom-to-operate analysis before commercial development. There is no compliance deadline or penalty information associated with this publication notice.

Source document (simplified)

← EPO Patent Bulletin

FORMATION OF ARRAYS OF PLANAR INTESTINAL CRYPTS POSSESSING A STEM/PROLIFERATTVE CELL COMPARTMENT AND DIFFERENTIATED CELL ZONE

Publication EP3802848A1 Kind: A1 Mar 25, 2026

Applicants

The University of North Carolina at Chapel Hill

Inventors

ALBRITTON, Nancy, L., WANG, Yuli, KIM, Raehyun

IPC Classifications

C12Q 1/08 20060101AFI20220131BHEP C12N 5/071 20100101ALI20220131BHEP A61L 27/00 20060101ALI20220131BHEP A61K 35/00 20060101ALI20220131BHEP C12M 3/00 20060101ALI20220131BHEP C12M 1/12 20060101ALI20220131BHEP C12M 1/42 20060101ALI20220131BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
EP3802848A1

Who this affects

Applies to
Pharmaceutical companies Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing 6211 Healthcare Providers 3254.1 Biotechnology
Activity scope
Patent Filing Biotechnology Research Cell Culture Methods
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
GxP
Topics
Biotechnology Healthcare Intellectual Property

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