Intestinal Crypt Arrays with Stem Cell and Differentiated Cell Zones - Patent
Summary
The European Patent Office published patent application EP3802848A1 for the University of North Carolina at Chapel Hill, covering methods for forming arrays of planar intestinal crypts possessing a stem/proliferative cell compartment and differentiated cell zone. The patent names inventors Albritton, Wang, and Kim, with IPC classifications in C12Q, C12N, A61L, and A61K. Designated states include all EU contracting states.
What changed
EPO published patent application EP3802848A1 titled 'Formation of arrays of planar intestinal crypts possessing a stem/proliferative cell compartment and differentiated cell zone' for the University of North Carolina at Chapel Hill. The invention covers methods for creating in vitro intestinal crypt arrays with defined cellular compartments, with inventors including Albritton, Wang, and Kim. The patent application is classified under multiple IPC codes including C12Q 1/08, C12N 5/071, and A61L 27/00, covering biological testing methods, cell cultures, and implant materials.
Patent holders should monitor for the patent grant decision, file national phase applications in desired jurisdictions (US, Japan, China, Korea), and conduct freedom-to-operate analysis before commercial development. There is no compliance deadline or penalty information associated with this publication notice.
Source document (simplified)
FORMATION OF ARRAYS OF PLANAR INTESTINAL CRYPTS POSSESSING A STEM/PROLIFERATTVE CELL COMPARTMENT AND DIFFERENTIATED CELL ZONE
Publication EP3802848A1 Kind: A1 Mar 25, 2026
Applicants
The University of North Carolina at Chapel Hill
Inventors
ALBRITTON, Nancy, L., WANG, Yuli, KIM, Raehyun
IPC Classifications
C12Q 1/08 20060101AFI20220131BHEP C12N 5/071 20100101ALI20220131BHEP A61L 27/00 20060101ALI20220131BHEP A61K 35/00 20060101ALI20220131BHEP C12M 3/00 20060101ALI20220131BHEP C12M 1/12 20060101ALI20220131BHEP C12M 1/42 20060101ALI20220131BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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