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HPV Vaccine Peptide Constructs with Ligand-Inducible Gene Switch Systems

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Summary

The USPTO published patent application US20260098063A1 titled 'Human Papillomavirus Vaccines and Uses of the Same.' The application covers engineered HPV molecular vaccine constructs incorporating ligand-inducible engineered gene switch systems for modulating expression of heterologous genes, such as cytokines, in host cells. The application was filed on July 7, 2025, by inventors including Douglas E. Brough and Cheryl G. Bolinger. Patent applications are published for informational purposes and do not grant enforceable rights until issued as a patent after examination.

What changed

The USPTO published patent application US20260098063A1 disclosing engineered HPV vaccine constructs and ligand-inducible engineered gene switch systems for modulating expression of heterologous genes such as cytokines in host cells. The application covers novel molecular vaccine constructs with CPC classifications including C07K 14/005, A61K 39/12, and A61K 39/292. Inventors include Douglas E. Brough, Cheryl G. Bolinger, Ramya Yarlagadda, Vinodhbabu Kurella, Prabakaran Ponraj, Simon Metenou, and Kuan-fu Ding.

Affected parties including pharmaceutical companies, vaccine developers, and biotechnology firms should monitor this publication for competitive intelligence purposes. Patent applications do not create compliance obligations but represent the beginning of the examination process that could eventually lead to granted patent rights covering HPV vaccine compositions and gene expression modulation systems.

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Archived snapshot

Apr 11, 2026

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← USPTO Patent Applications

HUMAN PAPILLOMAVIRUS VACCINES AND USES OF THE SAME

Application US20260098063A1 Kind: A1 Apr 09, 2026

Inventors

Douglas E. BROUGH, Cheryl G. BOLINGER, Ramya YARLAGADDA, Vinodhbabu KURELLA, Prabakaran PONRAJ, Simon METENOU, Kuan-fu DING

Abstract

Provided herein are engineered human papilloma virus (HPV) molecular vaccine constructs. Vaccine constructs can also include ligand-inducible engineered gene switch systems for modulating expression of heterologous genes, such as a cytokines, in host cells.

CPC Classifications

C07K 14/005 A61K 39/12 A61K 39/292 A61K 48/0066 C07K 14/02 C12N 7/00 C12N 15/861 C07K 2319/33 C12N 2710/20022 C12N 2710/20034

Filing Date

2025-07-07

Application No.

19261890

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Named provisions

HUMAN PAPILLOMAVIRUS VACCINES AND USES OF THE SAME

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260098063A1

Who this affects

Applies to
Pharmaceutical companies Manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent examination IP licensing Vaccine development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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