Harvard Patent - Automated Parallel Chromatography for Extracellular Vesicle Purification
Summary
USPTO published patent application US20260098244A1 from President and Fellows of Harvard College disclosing devices and methods for automated parallel chromatography for purification of extracellular vesicles from biological samples. The invention includes a pump, computing device, and a stand with columns containing resin and bottom wells or tubes. CPC classifications indicate applications in cell/vesicle technology and chromatography methods.
What changed
The USPTO published patent application US20260098244A1 from President and Fellows of Harvard College, filed July 10, 2025, disclosing devices and methods for automated chromatography analysis of multiple samples in parallel. The technology includes a pump, a computing device, and a stand with columns containing resin and a bottom portion with wells or tubes, designed for purification of extracellular vesicles from biological samples. CPC classifications include C12N 5/0634 (cell/vesicle technology), B01D 15/1885, B01D 15/34, and B01D 15/362 (chromatography).
Research institutions, biotech companies, and pharmaceutical firms developing extracellular vesicle purification technologies should review this application to assess potential freedom-to-operate implications if the patent grants. Competitors in the EV purification space may need to evaluate whether their existing or planned methods could fall within the scope of these claims.
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Apr 14, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
DEVICES, CHROMATOGRAPHY COLUMNS, METHODS FOR AUTOMATED CHROMATOGRAPHY IN PARALLEL AND METHODS FOR PURIFICATION OF EXTRACELLULAR VESICLES
Application US20260098244A1 Kind: A1 Apr 09, 2026
Assignee
President and Fellows of Harvard College
Inventors
Dmitry Ter-Ovanesyan, Tal Gilboa, Bogdan Budnik, David Kalish, George M. Church, David R. Walt
Abstract
The technology described herein is directed to devices and methods for automated chromatography analysis of multiple samples in parallel. The devices include a pump, a computing device, and a stand having an upper portion including columns containing a resin and a bottom portion including wells or tubes. The invention also provides disclosures for chromatography columns and methods for purification of extracellular vesicles from a biological sample.
CPC Classifications
C12N 5/0634 B01D 15/1885 B01D 15/34 B01D 15/362
Filing Date
2025-07-10
Application No.
19265231
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