Exon 44 Duchenne Muscular Dystrophy Cyclic Peptide Antisense
Summary
The USPTO published patent application US20260098262A9 covering compositions comprising a cyclic peptide and an antisense compound targeting exon 44 of the DMD gene for Duchenne Muscular Dystrophy treatment. The application was filed on August 30, 2022, under application number 18688083, listing nine inventors including Xiang Li, Ziqing Qian, and others. No compliance obligations or deadlines are associated with this publication.
This patent application publication represents a formal administrative record from the USPTO but does not create any regulatory obligations or deadlines for affected parties. Pharmaceutical and biotechnology companies developing exon-skipping therapies for DMD may wish to review the claims for potential freedom-to-operate implications.
What changed
The USPTO published patent application US20260098262A9 for compounds and methods designed to skip exon 44 of the DMD gene using cyclic peptide antisense compositions. The application covers therapeutic compositions comprising both cyclic peptides and antisense compounds targeting pre-mRNA sequences. No prior similar patent by the same inventors is referenced.
Pharmaceutical companies and biotechnology firms developing exon-skipping therapies for Duchenne Muscular Dystrophy should monitor this application's prosecution for potential impact on freedom-to-operate analyses. This publication does not impose compliance obligations or deadlines. Competitors pursuing similar DMD exon-skipping approaches may need to evaluate whether this application's claims overlap with their own development programs.
What to do next
- Monitor for updates on patent prosecution status
Archived snapshot
Apr 13, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
COMPOUNDS AND METHODS FOR SKIPPING EXON 44 IN DUCHENNE MUSCULAR DYSTROPHY
A9 US20260098262A9 Kind: A9 Apr 09, 2026
Inventors
Xiang Li, Ziqing Qian, Mahboubeh Kheirabadi, Mark Wysk, Natarajan Sethuraman, Wenlong Lian, Mahsweta Girgenrath, Nelsa Estrella
Abstract
Described herein in various embodiments are compositions comprising (a) a cyclic peptide; and (b) an antisense compound, wherein the antisense compound targets exon 44 of the DMD gene in a pre-mRNA sequence.
CPC Classifications
C12N 15/113 A61K 47/64 C12N 2310/3233 C12N 2310/3513
Filing Date
2022-08-30
Application No.
18688083
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