Changeflow GovPing Pharma & Drug Safety Exon 44 Duchenne Muscular Dystrophy Cyclic Pept...
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Exon 44 Duchenne Muscular Dystrophy Cyclic Peptide Antisense

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Summary

The USPTO published patent application US20260098262A9 covering compositions comprising a cyclic peptide and an antisense compound targeting exon 44 of the DMD gene for Duchenne Muscular Dystrophy treatment. The application was filed on August 30, 2022, under application number 18688083, listing nine inventors including Xiang Li, Ziqing Qian, and others. No compliance obligations or deadlines are associated with this publication.

This patent application publication represents a formal administrative record from the USPTO but does not create any regulatory obligations or deadlines for affected parties. Pharmaceutical and biotechnology companies developing exon-skipping therapies for DMD may wish to review the claims for potential freedom-to-operate implications.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

The USPTO published patent application US20260098262A9 for compounds and methods designed to skip exon 44 of the DMD gene using cyclic peptide antisense compositions. The application covers therapeutic compositions comprising both cyclic peptides and antisense compounds targeting pre-mRNA sequences. No prior similar patent by the same inventors is referenced.

Pharmaceutical companies and biotechnology firms developing exon-skipping therapies for Duchenne Muscular Dystrophy should monitor this application's prosecution for potential impact on freedom-to-operate analyses. This publication does not impose compliance obligations or deadlines. Competitors pursuing similar DMD exon-skipping approaches may need to evaluate whether this application's claims overlap with their own development programs.

What to do next

  1. Monitor for updates on patent prosecution status

Archived snapshot

Apr 13, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

COMPOUNDS AND METHODS FOR SKIPPING EXON 44 IN DUCHENNE MUSCULAR DYSTROPHY

A9 US20260098262A9 Kind: A9 Apr 09, 2026

Inventors

Xiang Li, Ziqing Qian, Mahboubeh Kheirabadi, Mark Wysk, Natarajan Sethuraman, Wenlong Lian, Mahsweta Girgenrath, Nelsa Estrella

Abstract

Described herein in various embodiments are compositions comprising (a) a cyclic peptide; and (b) an antisense compound, wherein the antisense compound targets exon 44 of the DMD gene in a pre-mRNA sequence.

CPC Classifications

C12N 15/113 A61K 47/64 C12N 2310/3233 C12N 2310/3513

Filing Date

2022-08-30

Application No.

18688083

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260098262A9

Who this affects

Applies to
Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent application filing Gene therapy research Exon-skipping therapeutics
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals

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