Changeflow GovPing Pharma & Drug Safety ERK Modulators Patent - Gen1E Lifesciences, Can...
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ERK Modulators Patent - Gen1E Lifesciences, Cancer Treatment

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Summary

USPTO granted patent US12595243B2 to GEn1E Lifesciences Inc. covering modulators of extracellular signal-regulated kinase (ERK) for treating cancer and pulmonary diseases. The patent includes 17 claims on the chemical compounds and pharmaceutical compositions. Inventors are Adam Galan, Ritu Lal, and Chakk Ramesha.

What changed

USPTO granted patent US12595243B2 for ERK modulators developed by GEn1E Lifesciences Inc., covering pharmaceutical compositions and methods of use for treating cancer and pulmonary diseases. The patent, classified under CPC codes C07D 333/48, A61P 35/00, and A61K 31/381, contains 17 claims. The filing date was October 18, 2024, with the grant becoming effective April 7, 2026.

For pharmaceutical companies and biotechnology researchers, this patent establishes exclusive rights for the assignee in the US market for ERK modulator applications. Competitors developing similar extracellular signal-regulated kinase modulators for cancer treatment should evaluate potential infringement risks and consider licensing negotiations. Academic and commercial research programs focusing on ERK pathway inhibition may need to establish design-around strategies or seek permission from GEn1E Lifesciences.

What to do next

  1. Review patent claims for potential licensing opportunities
  2. Assess Freedom to Operate for ERK-related research programs
  3. Monitor for related patent family publications

Archived snapshot

Apr 7, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Modulators of extracellular signal-regulated kinase

Grant US12595243B2 Kind: B2 Apr 07, 2026

Assignee

GEn1E Lifesciences Inc.

Inventors

Adam Galan, Ritu Lal, Chakk Ramesha

Abstract

Modulators of extracellular signal-regulated kinase, pharmaceutical compositions thereof, and uses of the compound and pharmaceutical compositions thereof for treating cancer and pulmonary diseases are disclosed.

CPC Classifications

C07D 333/48 A61P 35/00 A61K 31/381

Filing Date

2024-10-18

Application No.

18920162

Claims

17

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Last updated

Classification

Agency
USPTO
Published
April 7th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12595243B2

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Clinical investigators
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Pharmaceutical research Cancer treatment development Drug compound licensing
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare Public Health

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