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Patent Application: Disruption of GROOT Gene Function Increases Plant Biomass

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Summary

The USPTO has published a patent application (US20260085325A1) from the Salk Institute for Biological Studies detailing methods to enhance plant biomass and seed size by reducing the expression of GROOT1, GROOT2, and GROOT3 genes. The application describes compositions and transformed plants generated using these methods.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

This document is a published patent application from the USPTO, specifically application US20260085325A1, filed by the Salk Institute for Biological Studies. It describes methods and compositions for enhancing plant biomass and seed size by reducing the expression and/or activity of GROOT1, GROOT2, and/or GROOT3 genes. The application covers transformed plants and seeds resulting from these genetic modifications.

As this is a patent application, it does not impose direct regulatory obligations on companies. However, it may be of interest to companies involved in agricultural biotechnology, seed development, or plant science research. Compliance officers in these sectors should be aware of potential intellectual property developments in gene function modification for crop improvement.

Archived snapshot

Mar 27, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

DISRUPTION OF GROOT1, GROOT2, AND GROOT3 GENE FUNCTION INCREASES ROOT AND SHOOT BIOMASS

Application US20260085325A1 Kind: A1 Mar 26, 2026

Assignee

SALK INSTITUTE FOR BIOLOGICAL STUDIES

Inventors

Samsad Razzaque, Wolfgang Busch, Ashot Papikian, Ana Paez-Garcia

Abstract

Provided are methods and compositions for enhancing biomass, particularly shoot biomass and/or root biomass, and/or seed size in plants, by reducing expression and/or activity of GROOT1, GROOT2, and/or GROOT3 in plants. Also provided are plants and seeds generated using these methods. In some examples, reducing expression and/or activity includes introducing one or more exogenous nucleic acid molecules into a plant, plant part, or plant cell, thereby generating a transformed plant, plant part, or plant cell, wherein the one or more exogenous nucleic acid molecules reduce expression and/or activity of one or more of GROOT1, GROOT2, and GROOT3.

CPC Classifications

C12N 15/8262 C12N 9/226 C12N 15/11 C12N 15/8205 C12N 15/8213 C12N 2310/20

Filing Date

2025-09-23

Application No.

19337581

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Last updated

Classification

Agency
USPTO
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260085325A1

Who this affects

Applies to
Drug manufacturers Food manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Biotechnology Research Gene Expression Modification
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Research & Development
Topics
Biotechnology Agriculture

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