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DISARM Therapeutics patent, SARM1 inhibitors, neuroprotection

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DISARM Therapeutics patent, SARM1 inhibitors, neuroprotection

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Apr 7, 2026

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Methods and compositions for neuroprotection

Grant US12595481B2 Kind: B2 Apr 07, 2026

Assignee

DISARM THERAPEUTICS, INC.

Inventors

Liza Leventhal, Thomas Engber, Raul Eduardo Krauss, Rajesh Devraj, Robert Owen Hughes, Todd Bosanac, Sudhir Agrawal, Marco A. Passini

Abstract

The present invention relates to compositions and methods for treating neurodegeneration and neurodegenerative diseases associated with axonal degeneration. Neurodegeneration and neurodegenerative diseases associated with axonal degeneration are treated with therapies comprising SARM1 inhibitors such as SARM1 antisense oligonucleotides.

CPC Classifications

C12N 15/113 C12N 2310/11 C12N 2310/3125 C12N 2310/314 C12N 2310/315 C12N 2310/316 C12N 2310/531 C12N 2310/322 C12N 2310/341 C12N 2310/345 C12N 2310/3525 A61K 31/7088

Filing Date

2020-11-25

Application No.

17778567

Claims

18

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