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Deuterated Organic Compounds for Schizophrenia and Depression Treatment

Favicon for changeflow.com USPTO Patent Applications - Organic Chemistry (C07D)
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Summary

The USPTO published patent application US20260098011A1 covering deuterated organic compounds of Formula I and II for modulating dopamine and serotonin neurotransmission. The compounds are directed toward treating disorders including schizophrenia and depression. The application was filed on June 11, 2025, under application number 19235237.

What changed

The USPTO published patent application US20260098011A1 disclosing deuterated organic compounds of Formula I and II useful for modulating dopamine and serotonin neurotransmission. The compounds are directed toward treating schizophrenia, depression, and related neuropsychiatric disorders. The application includes processes for compound preparation, pharmaceutical compositions, and therapeutic uses.

Pharmaceutical companies and biotech firms developing neuropsychiatric treatments should review this publication to assess potential overlaps with their own R&D programs and freedom-to-operate positions. The deuterated compound approach may offer IP differentiation opportunities for drug developers targeting CNS disorders. Clinical development and regulatory approval would be required before any therapeutic use.

What to do next

  1. Monitor patent prosecution for claims scope
  2. Review therapeutic applications in neuropsychiatric drug pipelines
  3. Assess IP landscape for deuterated compound innovations

Archived snapshot

Apr 9, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF

Application US20260098011A1 Kind: A1 Apr 09, 2026

Inventors

Krishna VADODARIA, Kimberly VANOVER, Vikram SUDARSAN, David GARVEY

Abstract

Provided are compounds of Formula I and Formula II, described herein, processes for their preparation, their use as pharmaceuticals, and pharmaceutical compositions comprising them and intermediates used in their preparation. Compounds of Formula I and Formula II are useful, for instance, in modulating dopamine and serotonin neurotransmission and treating disorders that may benefit from the same, such as schizophrenia and depression.

CPC Classifications

C07D 207/14 A61K 31/40 A61K 31/402 A61P 25/22 A61P 25/24 C07B 59/004 C07D 207/09 C07B 2200/05

Filing Date

2025-06-11

Application No.

19235237

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260098011A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent application filing CNS drug research Pharmaceutical composition development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Regulatory Affairs
Compliance frameworks
GxP
Topics
Pharmaceuticals Healthcare

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