DEA Detroit Public Safety Alert: Cychlorphine Synthetic Opioid Warning
Summary
DEA Detroit Division issued a public safety alert warning law enforcement, first responders, and medical professionals about Cychlorphine, a powerful synthetic opioid identified through DEA lab testing. The substance appears in powder form and has been found mixed into counterfeit pills, presenting serious risks including sedation, respiratory depression, and death.
What changed
The DEA Detroit Division issued a public safety alert regarding Cychlorphine, a newly identified synthetic opioid appearing in DEA laboratory testing. The substance presents as a white powder and has been detected mixed into counterfeit pills, posing risks of severe sedation, respiratory depression, and potentially fatal outcomes. This alert serves as an early warning to law enforcement, first responders, and healthcare providers about an emerging threat in the illicit drug supply.
Law enforcement agencies and public health authorities should update overdose response protocols to account for synthetic opioids that may resist standard naloxone dosing. First responders should exercise increased caution when encountering unidentified white powders or counterfeit pharmaceuticals. Healthcare providers, particularly emergency department staff, should be prepared for atypical overdose presentations associated with high-potency synthetic opioids.
What to do next
- Ensure first responders are trained to recognize Cychlorphine-related overdose symptoms
- Advise personnel to use appropriate PPE when handling suspected Cychlorphine substances
- Remind staff that naloxone may be less effective against synthetic opioids of unknown potency
Archived snapshot
Apr 8, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Post
Have you heard of Cychlorphine? It's a powerful synthetic opioid that is showing up in DEA lab testing. It comes in powder form and can be added to counterfeit pills. It can cause sedation and respiratory depression, leading to death. @TheJusticeDept @DEAHQ ALT
1:41 pm · 7 Apr 2026
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