Changeflow GovPing Pharma & Drug Safety Oxidation-Resistant AAT Gene Therapy Patent App...
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Oxidation-Resistant AAT Gene Therapy Patent Application

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office published patent application EP3600345A1 for Cornell University covering oxidation-resistant AAT (alpha-1 antitrypsin) gene therapy compositions. The application names eight inventors and claims priority dates back to 2020. The patent is designated across 33 European Patent Convention member states including major pharmaceutical markets.

What changed

The EPO published European patent application EP3600345A1 for Cornell University's oxidation-resistant AAT gene therapy, with international patent classification spanning A61K (medicinal preparations), C07K (peptides), and C12N (microorganisms/genes). The application designates 33 EPC contracting states covering the EU, UK, Switzerland, Norway, and other European jurisdictions. Priority dates trace back to November 2020, indicating this represents a continuation or divisional of earlier filings.

Patent publications are informational filings that do not impose compliance obligations. Competitors developing AAT gene therapy products should review the claims to assess potential freedom-to-operate implications. The publication initiates a nine-month opposition period following patent grant. No action is required for parties not engaged in related technology development.

Source document (simplified)

← EPO Patent Bulletin

OXIDATION-RESISTANT AAT GENE THERAPY

Publication EP3600345A1 Kind: A1 Mar 25, 2026

Applicants

Cornell University

Inventors

CRYSTAL, Ronald G., STILES, Katie, SOSULSKI, Meredith, KAMINSKY, Stephen M., SONDHI, Dolan, DE, Bishnu, ROSENBERG, Jonathan

IPC Classifications

A61K 31/712 20060101AFI20201127BHEP A61K 48/00 20060101ALI20201127BHEP C07K 14/81 20060101ALI20201127BHEP C12N 15/00 20060101ALI20201127BHEP C12N 15/09 20060101ALI20201127BHEP C12N 15/63 20060101ALI20201127BHEP C12N 15/86 20060101ALI20201127BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

OXIDATION-RESISTANT AAT GENE THERAPY

Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP3600345A1

Who this affects

Applies to
Pharmaceutical companies Research institutions Biotechnology companies
Industry sector
3254.1 Biotechnology 3254 Pharmaceutical Manufacturing 6111 Higher Education
Activity scope
Biopharmaceutical Patent Filing Gene Therapy Development Patent Portfolio Management
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Biotechnology Healthcare

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