Copper-Chelating Butanediamine Derivatives Patent EP3823977A1
Summary
The European Patent Office published application EP3823977A1 for (pyridinylmethyl)butanediamine derivatives capable of chelating copper, filed by Cold Spring Harbor Laboratory and Depymed, Inc. The patent covers pharmaceutical compounds with applications in liver diseases, neurological conditions, and cancer treatment. Designated states include all EU member states plus EEA countries.
What changed
The European Patent Office granted patent EP3823977A1 for novel (pyridinylmethyl)butanediamine compounds with copper-chelating properties. The patent application was filed by Cold Spring Harbor Laboratory and Depymed, Inc., with inventors including Nicholas Tonks, Navasona Krishnan, and Andreas Grill. The compounds are classified under multiple therapeutic categories including liver diseases (A61P 1/16), neurological conditions (A61P 25/00), and cancer (A61P 35/00).
For pharmaceutical developers and researchers in copper metabolism disorders, this patent establishes intellectual property protection for copper-chelating butanediamine derivatives. Companies developing treatments for Wilson's disease, Alzheimer's disease, or cancer therapies targeting copper-dependent pathways should assess freedom-to-operate before commencing related R&D programs.
What to do next
- Monitor freedom-to-operate if developing copper chelation therapies
- Review patent claims for potential licensing opportunities
Archived snapshot
Apr 8, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
(PYRIDINYLMETHYL)BUTANEDIAMINE DERIVATIVES THAT CHELATE COPPER
Publication EP3823977A1 Kind: A1 Apr 01, 2026
Applicants
Cold Spring Harbor Laboratory, Depymed, Inc.
Inventors
TONKS, Nicholas, KRISHNAN, Navasona, GRILL, Andreas
IPC Classifications
C07J 9/00 20060101AFI20260114BHEP C07J 43/00 20060101ALI20260114BHEP C07D 401/12 20060101ALI20260114BHEP A61P 1/16 20060101ALI20260114BHEP A61P 25/00 20060101ALI20260114BHEP A61P 35/00 20060101ALI20260114BHEP C07D 213/38 20060101ALI20260114BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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Source
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