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Collagenase Compositions for Orthodontic Procedures Patent Application

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Published December 1st, 2025
Detected March 26th, 2026
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Summary

The USPTO has published a patent application detailing compositions comprising collagenase and their uses in orthodontic procedures. The application, filed by inventors from Israel, describes potential uses for recombinant collagenase and modified forms thereof in dental treatments.

What changed

This document is a published patent application (US20260083641A1) from the USPTO concerning compositions containing collagenase for use in orthodontic procedures. The application specifically mentions recombinant collagenase and modified forms, including those with amino acid truncations or substitutions, as potential therapeutic agents for dental applications.

As this is a patent application, it does not impose direct regulatory obligations or compliance deadlines on regulated entities. However, it signals potential future developments in the pharmaceutical and medical device sectors related to dental treatments. Companies involved in drug development, medical devices, or orthodontic products may wish to monitor the progress of this patent application and related technologies for competitive intelligence and potential licensing opportunities.

Source document (simplified)

← USPTO Patent Applications

COMPOSITIONS COMPRISING COLLAGENASE AND USES THEREOF IN ORTHODONTIC PROCEDURES

Application US20260083641A1 Kind: A1 Mar 26, 2026

Inventors

Maayan GAL, Orel COHEN, Diva LUGASSY, Itzhak BINDERMAN, Evgeny WEINBERG

Abstract

Provided herein compositions including collagenase, and uses thereof in orthodontic procedures, wherein the compositions may include recombinant collagenase and/or modified forms of recombinant collagenase having amino acid(s) truncation or substitutions.

CPC Classifications

A61K 6/50 A61K 6/69 C12Y 304/24003

Filing Date

2025-12-01

Application No.

19404309

View original document →

Named provisions

COMPOSITIONS COMPRISING COLLAGENASE AND USES THEREOF IN ORTHODONTIC PROCEDURES

Classification

Agency
USPTO
Published
December 1st, 2025
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260083641A1
Docket
19404309

Who this affects

Applies to
Drug manufacturers Medical device makers
Industry sector
3254 Pharmaceutical Manufacturing 3345 Medical Device Manufacturing
Activity scope
Drug Development Medical Device Innovation
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
R&D
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Pharmaceuticals Medical Devices

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