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BlueRock Therapeutics LP Graft-Related Arrhythmia Treatment Patent Application

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Summary

The USPTO published patent application US20260097012A1 by BlueRock Therapeutics LP on April 9, 2026, disclosing methods of treating or preventing graft-related arrhythmia in cardiac graft patients by administering combinations of anti-arrhythmic agents including amiodarone, metoprolol, ivabradine, and mexiletine. The application was originally filed on September 27, 2023. This published application makes the invention publicly available for examination and potential licensing or competitive intelligence purposes.

What changed

The USPTO published patent application US20260097012A1 disclosing pharmaceutical compositions and methods for treating graft-related arrhythmia in cardiac graft patients. The claimed invention involves administering combinations of anti-arrhythmic agents such as amiodarone, metoprolol, ivabradine, and mexiletine to subjects receiving cardiac grafts.

For pharmaceutical and biotech companies developing cardiac therapies or cell-based treatments, this published application establishes prior art and may affect freedom-to-operate analyses. Competitors should review the claims for overlap with their own development programs. Patent monitoring systems should be updated to track prosecution of this application toward potential grant.

What to do next

  1. Monitor for updates on patent prosecution status
  2. Review claims for potential freedom-to-operate implications
  3. Assess competitive landscape for cardiac graft arrhythmia treatments

Archived snapshot

Apr 13, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

COMPOSITIONS AND METHODS FOR TREATING GRAFT-RELATED ARRHYTHMIA

Application US20260097012A1 Kind: A1 Apr 09, 2026

Assignee

BlueRock Therapeutics LP

Inventors

Ibrahim Domian, Rocco Romagnuolo

Abstract

Provided herein are methods of treating or preventing an arrhythmia in a cardiac graft patient, wherein the method comprises administering combinations of anti-arrhythmic agents (e.g., amiodarone, metoprolol, ivabradine, and/or mexiletine) to the subject in need thereof.

CPC Classifications

A61K 31/343 A61K 31/138 A61K 31/166 A61K 31/167 A61K 31/277 A61K 31/55 A61K 35/34 A61P 9/06

Filing Date

2023-09-27

Application No.

19115880

View original document →

Named provisions

Compositions and Methods for Treating Graft-Related Arrhythmia

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260097012A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Patent applications Pharmaceutical research Biotechnology research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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