Changeflow GovPing Pharma & Drug Safety Bispecific PD1-TIM3 Antibodies
Routine Notice Added Final

Bispecific PD1-TIM3 Antibodies

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office published patent application EP3649155A1 for Merus B.V., covering bispecific antibodies targeting PD1 and TIM3 antigens. The patent names six inventors and designates 37 European states for protection. This is a standard patent publication providing public notice of intellectual property rights in the pharmaceutical biotechnology space.

What changed

The EPO published patent EP3649155A1 for Merus B.V. (Utrecht, Netherlands), claiming bispecific anti-PD1 and anti-TIM3 antibodies for therapeutic use. The application names inventors GEUUIJEN, KLOOSTER, DE KRUIF, TACKEN, THROSBY, and LOGTENBERG. IPC classifications indicate pharmaceutical (A61K) and protein (C07K) technology focus, with designations covering all major EU member states and extended European states.

Patent publications do not impose compliance obligations on third parties. Pharmaceutical companies and biotechnology firms developing similar bispecific antibody technologies should review the claims to assess potential freedom-to-operate implications or licensing needs. This publication does not require any regulatory action from industry participants.

Source document (simplified)

← EPO Patent Bulletin

BISPECIFIC ANTI PD1-ANTI TIM3 ANTIBODIES

Publication EP3649155A1 Kind: A1 Mar 25, 2026

Applicants

Merus B.V.

Inventors

GEUIJEN, Cecilia Anna Wilhelmina, KLOOSTER, Rinse, DE KRUIF, Cornelis Adriaan, TACKEN, Paulus Johannes, THROSBY, Mark, LOGTENBERG, Ton

IPC Classifications

C07K 16/28 20060101AFI20190111BHEP A61K 39/00 20060101ALI20190111BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP3649155A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Biopharmaceutical Research Antibody Development Immunotherapy
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Compliance
Topics
Pharmaceuticals Biotechnology

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