Biallelic Knockout CISH Gene, RNA Compositions
Summary
USPTO published patent application US20260097121A1 by inventor Rafi Emmanuel covering RNA compositions with guide sequences targeting the CISH gene for biallelic knockout. The application includes sequences defined by SEQ ID NOs 1-6838 and methods for their use. Filing date was September 18, 2023, under application number 19113098.
What changed
USPTO published patent application US20260097121A1 covering compositions comprising RNA molecules with guide sequences of 17-50 contiguous nucleotides targeting CISH gene sequences defined by SEQ ID NOs 1-6838, along with associated methods and uses.
Affected parties including biotech researchers, gene therapy developers, and pharmaceutical companies should monitor this application for potential licensing opportunities or freedom-to-operate considerations in CISH-related gene editing technologies.
What to do next
- Monitor for patent grant status
Archived snapshot
Apr 14, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Biallelic Knockout of CISH
Application US20260097121A1 Kind: A1 Apr 09, 2026
Inventors
Rafi EMMANUEL
Abstract
Compositions comprising an RNA molecule comprising a guide sequence portion having 17-50 contiguous nucleotides containing nucleotides in the sequence set forth in any one of SEQ ID NOs: 1-6838 and methods and uses thereof.
CPC Classifications
A61K 40/34 A61K 40/11 C12N 9/226 C12N 15/11 C12N 15/907 C12N 2310/20
Filing Date
2023-09-18
Application No.
19113098
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