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Biallelic CIITA Knockout Patent, 34199 RNA Sequences

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Summary

USPTO published patent application US20260097123A1 for compositions and methods for biallelic CIITA knockout using RNA molecules comprising guide sequences of 17-50 nucleotides. The application covers 34,199 sequences (SEQ ID NOs 1-34199). Inventor: Rafi Emmanuel. Filing date: September 19, 2023.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

USPTO published patent application US20260097123A1 for compositions and methods for biallelic CIITA knockout using RNA molecules with guide sequences (17-50 nucleotides). The application covers 34,199 sequences (SEQ ID NOs 1-34199) and was filed September 19, 2023 by inventor Rafi Emmanuel. This publication makes the application claims publicly available for examination purposes.

Entities in biotechnology and pharmaceutical research should monitor this application as it could impact the intellectual property landscape for gene editing technologies targeting CIITA.

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Archived snapshot

Apr 14, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

Biallelic Knockout of CIITA

Application US20260097123A1 Kind: A1 Apr 09, 2026

Inventors

Rafi EMMANUEL

Abstract

Compositions comprising an RNA molecule comprising a guide sequence portion having 17-50 contiguous nucleotides containing nucleotides in the sequence set forth in any one of SEQ ID NOs: 1-34199 and methods and uses thereof.

CPC Classifications

A61K 40/50 A61K 40/11 C12N 9/226 C12N 15/11 C12N 15/907 C12N 2310/20

Filing Date

2023-09-19

Application No.

19113015

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260097123A1

Who this affects

Applies to
Drug manufacturers Clinical investigators
Industry sector
3254.1 Biotechnology
Activity scope
Patent application Gene therapy research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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