Patent Application: Benzamide Compounds for SARS-CoV-2 PLpro Inhibition
Summary
The USPTO has published a new patent application (US20260085063A1) detailing benzamide compounds and methods for inhibiting SARS-CoV-2 PLpro. The application was filed on August 19, 2025, by inventors Jun Wang, Bin Tan, and Prakash Daulat Jadhav.
What changed
This document is a publication of a United States patent application, specifically US20260085063A1, filed on August 19, 2025. The application describes novel benzamide compounds and their use in inhibiting the SARS-CoV-2 papain-like protease (PLpro), aiming to promote antiviral effects and treat viral infections. The inventors listed are Jun Wang, Bin Tan, and Prakash Daulat Jadhav.
As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on regulated entities. However, it signifies potential future intellectual property rights and may influence research and development in the pharmaceutical sector. Companies operating in this space should monitor the progress of this patent application and related filings for potential licensing opportunities or competitive landscape shifts.
Source document (simplified)
BENZAMIDE COMPOUNDS AND METHODS OF USE THEREOF
Application US20260085063A1 Kind: A1 Mar 26, 2026
Inventors
Jun Wang, Bin Tan, Prakash Daulat Jadhav
Abstract
The present disclosure relates, in part, to SARS-CoV-2 papain-like protease (PLpro) inhibitor compounds of Formula (I), pharmaceutical compositions thereof, and methods of using the same for promoting an antiviral effect in a subject and/or treating, preventing, and/or ameliorating a viral infection in a subject:
CPC Classifications
C07D 403/14 A61K 31/4155 A61K 31/427 A61K 31/438 A61K 31/454 A61K 31/496 A61K 31/4995 A61K 31/5377 A61K 31/541 A61P 31/14 C07D 231/12 C07D 401/14 C07D 403/10 C07D 405/14 C07D 413/14 C07D 417/10 C07D 471/10 C07D 487/04 C07D 487/08
Filing Date
2025-08-19
Application No.
19304124
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