BCL-XL/BCL-2 Degraders and Uses Thereof
Summary
The USPTO published patent application US20260092057A1 for BCL-XL/BCL-2 degrader compounds and methods of using the same for treating conditions such as cancer. The application was filed on May 12, 2023, by inventors including Huijun Dong, Bin Yang, and others, and covers novel chemical compositions under CPC classifications including C07D 417/12, C07D 471/04, and related therapeutic uses.
What changed
The USPTO published a patent application (US20260092057A1) for BCL-XL/BCL-2 degrader compounds and their uses in treating diseases such as cancer (A61P 35/00). The application covers novel heterocyclic compounds classified under multiple C07D subclasses and pharmaceutical compositions containing them. The compounds are potential therapeutic agents targeting anti-apoptotic Bcl-2 family proteins.
Pharmaceutical companies and drug manufacturers developing oncology therapeutics should review this published application to assess potential freedom-to-operate considerations or licensing opportunities. Patent applications do not impose compliance obligations but represent published intellectual property claims that may affect competitive landscape. No regulatory deadlines or penalties apply to this notice.
Archived snapshot
Apr 2, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
BCL-XL/BCL-2 DEGRADERS AND USES THEREOF
Application US20260092057A1 Kind: A1 Apr 02, 2026
Inventors
Huijun Dong, Bin Yang, Lewis Dale Pennington, Eamon Comer, Melissa Ford, Robert Aversa, Matthew M. Weiss, Xiao Zhu, Thijs Beuming
Abstract
The present invention provides compounds, compositions thereof, and methods of using the same.
CPC Classifications
C07D 417/12 A61K 31/496 A61K 31/635 A61P 35/00 C07D 207/16 C07D 401/12 C07D 417/14 C07D 471/04 C07D 471/08 C07D 471/10 C07D 487/04 C07D 487/08 C07D 487/10 C07D 519/00
Filing Date
2023-05-12
Application No.
18864802
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