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Novel Anti-Asporin Antibody Targets Fibrotic Disease Including Idiopathic Pulmonary Fibrosis

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Summary

USPTO published patent application US20260098083A1 disclosing a novel antibody binding specifically to Asporin protein for predicting onset and treating fibrotic diseases, including idiopathic pulmonary fibrosis. Inventors are Hogeun Yoon and Soo-Yeon Park. The application was filed on September 20, 2023.

What changed

USPTO published patent application US20260098083A1 disclosing an anti-Asporin antibody for predicting and treating fibrotic diseases, including idiopathic pulmonary fibrosis. The invention provides an antibody that binds specifically to Asporin protein involved in fibrosis pathways, offering a diagnostic, preventive, and therapeutic approach where no clear pathogenic mechanism has been established.

For biotechnology and pharmaceutical companies, this patent represents a potential therapeutic target for fibrosis treatment. Researchers and drug developers should monitor this application's prosecution for claim scope and evaluate whether Asporin inhibition represents a viable pipeline opportunity. Patent examiners may cite this reference in related antibody or fibrosis therapy applications.

What to do next

  1. Monitor for patent grant or office action
  2. Evaluate licensing opportunities for Asporin-targeting antibody development

Archived snapshot

Apr 10, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

Novel Antibody For Prevention Or Treatment Of Fibrotic Disease

Application US20260098083A1 Kind: A1 Apr 09, 2026

Inventors

Hogeun YOON, Soo-Yeon PARK

Abstract

The present invention relates to a method for prevention or treatment of fibrotic disease, wherein an antibody binding specifically to Asporin protein involved in fibrosis is used for predicting the onset of fibrotic disease or for inhibiting the activity of the corresponding protein. The present invention provides an effective antibody that can be used for the diagnosis, prevention, and treatment of idiopathic pulmonary fibrosis, a condition for which efficient treatment methods have been absent because a clear pathogenic mechanism is not known therefor. In addition, the present invention can be advantageously used to effectively block fibrosis in various tissues by ultimately providing a fundamental inhibitory method for pathological fibrosis mechanisms.

CPC Classifications

C07K 16/18 A61P 7/04 C07K 2317/76

Filing Date

2023-09-20

Application No.

19112732

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260098083A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Healthcare providers
Industry sector
3254.1 Biotechnology
Activity scope
Patent publishing Biotechnology research Antibody development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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