Amidines and amidine analogs for bacterial infection treatment
Summary
The USPTO granted Patent US12595251B2 to Georgia State University Research Foundation, covering amidine compounds and methods for treating bacterial infections or potentiating antibiotics. The patent names Binghe Wang, David W. Boykin, Manjusha Roy Choudhary, Arvind Kumar, Bingchen Yu, and Mengyuan Zhu as inventors. The patent, with 10 claims, covers CPC classifications including C07D compounds and A61P 31/04 (anti-infectives).
What changed
The USPTO issued Patent US12595251B2 granting Georgia State University Research Foundation exclusive rights to amidine compounds for bacterial infection treatment and antibiotic potentiation. The patent covers 10 claims relating to compound compositions and methods of use under CPC classifications C07D 403/12, C07D 409/04, A61K 31/155, and A61P 31/04. The filing date was June 13, 2019, with application number 17251658.
For pharmaceutical companies and researchers in antibiotic development, this grant establishes intellectual property barriers around amidine-based antibiotic potentiation technology. Healthcare providers and drug manufacturers should conduct Freedom to Operate analyses before developing or commercializing related therapeutic approaches. The patent's broad claim scope covering both standalone treatment and antibiotic potentiation may affect licensing strategies and research directions in the anti-infectives space.
What to do next
- Monitor patent databases for Freedom to Operate analysis
- Review potential licensing opportunities for antibiotic potentiation technology
- Assess impact on antibiotic development programs
Archived snapshot
Apr 7, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics
Grant US12595251B2 Kind: B2 Apr 07, 2026
Assignee
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Inventors
Binghe Wang, David W. Boykin, Manjusha Roy Choudhary, Arvind Kumar, Bingchen Yu, Mengyuan Zhu
Abstract
Compounds and methods for the treatment of a bacterial infection or the potentiation of an antibiotic in treating a bacterial infection are described herein.
CPC Classifications
C07D 403/12 C07D 409/04 C07D 213/30 C07D 231/06 C07D 235/18 C07D 239/06 C07D 401/06 C07D 403/10 C07D 409/10 C07D 409/14 A61K 45/06 A61K 31/155 A61K 2300/00 C07C 217/58 C07C 257/18 C07C 321/28 C07C 323/62 C07C 259/18 C07C 279/18 A61P 31/04
Filing Date
2019-06-13
Application No.
17251658
Claims
10
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Source
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