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ALPHA-1062 Pharmaceutical Composition for Treating Traumatic Brain Injury

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Summary

USPTO granted Patent US12589099B2 to Alpha Cognition Inc. for a pharmaceutical composition containing ALPHA-1062 (or salt thereof) for treating confirmed or suspected traumatic brain injury (TBI). The patent includes 27 claims covering transmucosal/intranasal administration methods and a multi-use dispenser configuration. The composition may be self-preserving and anti-microbial.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

USPTO issued Patent US12589099B2 on March 31, 2026, granting Alpha Cognition Inc. exclusive rights to ALPHA-1062 pharmaceutical compositions for treating traumatic brain injury. The patent (filed November 25, 2022, Application No. 18549309) contains 27 claims covering the composition, treatment methods using transmucosal/intranasal administration, and a multi-use dispenser device. CPC classifications include A61P 25/00, A61K 31/55, and A61K 9/0043.

Patent grants do not impose compliance obligations on pharmaceutical companies, but organizations developing TBI treatments should conduct freedom-to-operate analyses to assess potential infringement risks. Generic drug manufacturers and biotech firms pursuing similar TBI therapeutics should review this patent's claims to understand the scope of ALPHA-1062 protection before advancing competing programs through clinical development.

Archived snapshot

Mar 31, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Alpha-1062 for treating traumatic brain injury

Grant US12589099B2 Kind: B2 Mar 31, 2026

Assignee

Alpha Cognition Inc.

Inventors

Denis G. Kay

Abstract

A pharmaceutical composition including a compound ALPHA-1062 or salt thereof, or a compound ALPHA-1062 or salt thereof, for use in the treatment of confirmed or suspected traumatic brain injury (TBI) in a subject. In embodiments, the composition is administered transmucosally, such as intranasally, and/or the composition is self-preserving and anti-microbial. Also disclosed is a multi-use dispenser configured for intranasal or transmucosal administration of a pharmaceutical composition including ALPHA-1062 or salt thereof. Also disclosed is a method of treating traumatic brain injury (TBI) in a subject including administering a therapeutically effective amount of a pharmaceutical composition including ALPHA-1062 or salt thereof.

CPC Classifications

A61P 25/00 A61K 31/55 A61K 9/0043

Filing Date

2022-11-25

Application No.

18549309

Claims

27

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Named provisions

Pharmaceutical Composition Treatment of Traumatic Brain Injury Multi-use Dispenser Transmucosal Administration Method

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Last updated

Classification

Agency
USPTO
Published
March 31st, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12589099B2

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Pharmaceutical Manufacturing Drug Development Intellectual Property Licensing
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
GxP
Topics
Healthcare Intellectual Property

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