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Anti-human P40 protein domain antibody and use thereof

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Summary

USPTO granted Patent US12595300B2 to Akeso Biopharma, Inc. covering an anti-human P40 protein domain antibody for treating autoimmune diseases. The patent includes 20 claims with specific amino acid sequences for heavy and light chain variable regions (SEQ ID NOs 1, 24 for heavy chain; SEQ ID NOs 6, 11, 13, 15, 17, 25 for light chain).

What changed

USPTO granted Patent US12595300B2 to Akeso Biopharma, Inc. for an antibody targeting human P40 protein for autoimmune disease treatment. The patent protects specific heavy chain and light chain variable region amino acid sequences and their use in treating autoimmune conditions, with 20 claims total.

Affected parties including pharmaceutical companies, biotechnology firms, and researchers working on P40-targeting therapies should be aware that this patent grants Akeso Biopharma exclusive rights to these specific antibody sequences for autoimmune disease applications. Parties developing competing therapies targeting the same protein may need to obtain licenses or design alternative antibody sequences to avoid infringement.

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Archived snapshot

Apr 7, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Anti-human P40 protein domain antibody and use thereof

Grant US12595300B2 Kind: B2 Apr 07, 2026

Assignee

Akeso Biopharma, Inc.

Inventors

Yu Xia, Zhongmin Maxwell Wang, Peng Zhang, Baiyong Li

Abstract

Provided is an antibody for the treatment or prevention of autoimmune diseases, comprising a heavy chain variable region represented by SEQ ID NO: 1 or SEQ ID NO: 24, and a light chain variable region represented by SEQ ID NO: 6, SEQ ID NO: 11, SEQ ID NO: 13, SEQ ID NO: 15, SEQ ID NO: 17, or SEQ ID NO: 25.

CPC Classifications

C07K 16/244 C07K 2317/31 C07K 2317/565 C07K 2317/567 C07K 2317/76 C07K 2317/92 C07K 2319/30 A61K 47/6845 A61K 2039/505 A61P 37/06

Filing Date

2020-07-28

Application No.

17631797

Claims

20

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Last updated

Classification

Agency
USPTO
Published
April 7th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12595300B2

Who this affects

Applies to
Pharmaceutical companies Investors Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent examination IP licensing Therapeutic development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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