AAV Gene Therapy for Hypertrophic Cardiomyopathy
Summary
USPTO published patent application US20260091139A1 for AAV gene therapy compositions targeting reduced cardiac myosin binding protein C levels in subjects with hypertrophic cardiomyopathy. The application (filed September 22, 2023, Application No. 19113698) names six inventors including Peter Cameron Colosi and Eduard Ayuso. This is a publication notice with no immediate compliance obligations.
What changed
USPTO published patent application US20260091139A1 disclosing AAV gene therapy vectors and methods for treating hypertrophic cardiomyopathy by addressing reduced levels of functional cardiac myosin binding protein C. The application covers gene therapy compositions and treatment methods with CPC classifications including A61K 48/0058 and C12N 15/86. The 2026 publication date follows the standard 18-month publication window from the September 2023 filing date.
This is a patent application publication, not a regulatory rule or enforcement action. It creates no compliance obligations, deadlines, or penalties. Pharmaceutical companies, biotech firms, and healthcare researchers developing gene therapies for cardiac conditions may wish to review the claims for potential licensing opportunities or freedom-to-operate considerations. No action is required for regulatory compliance purposes.
Archived snapshot
Apr 2, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
TREATMENT OF CARDIOMYOPATHY WITH AAV GENE THERAPY VECTORS
Application US20260091139A1 Kind: A1 Apr 02, 2026
Inventors
Peter Cameron COLOSI, Pooja AGARWAL, Wesley YONEMOTO, Sergio VIEDMA-GONZALEZ, Eduard AYUSO, Thomas VOIT, Valeria RICOTTI
Abstract
Provided herein are gene therapy compositions and methods of treating reduced levels of functional cardiac myosin binding protein C in a subject having hypertrophic cardiomyopathy.
CPC Classifications
A61K 48/0058 A61K 38/1719 A61P 9/10 C12N 15/86 C12N 2750/14143 C12N 2750/14152
Filing Date
2023-09-22
Application No.
19113698
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