Changeflow GovPing Healthcare NIH Terminates Minority Biomedical Research Sup...
Priority review Rule Removed Final

NIH Terminates Minority Biomedical Research Support Program

Favicon for www.regulations.gov Regs.gov: National Institutes of Health
Published September 25th, 2025
Detected March 15th, 2026
Email

Summary

The Department of Health and Human Services (HHS), through the National Institutes of Health (NIH), is repealing the regulation for the Minority Biomedical Research Support (MBRS) program. This action is effective September 25, 2025, and aligns with recent Supreme Court decisions and executive orders concerning discrimination and DEI programs.

What changed

The Department of Health and Human Services (HHS), in conjunction with the National Institutes of Health (NIH), has issued a final rule to repeal the regulation governing the Minority Biomedical Research Support (MBRS) program. This termination is a direct response to Executive Orders 14173 and 14151, and the Supreme Court's ruling in Students for Fair Admissions, Inc. v. President and Fellows of Harvard College, which found race-based affirmative action programs to be in violation of the Equal Protection Clause and Title VI of the Civil Rights Act. The MBRS program, which prioritized racial classifications in awarding federal research funding, is deemed contrary to these legal precedents.

This repeal means that the MBRS program will cease to exist, and the associated regulation at 42 CFR Part 52c will be removed. Institutions that previously relied on or participated in the MBRS program will need to adjust their strategies for seeking federal research funding. While the rule is effective September 25, 2025, no specific compliance deadline for entities is mentioned beyond the effective date of the repeal itself. The agency has cited good cause for dispensing with notice-and-comment procedures, deeming them impractical and unnecessary given the direct conflict with established legal precedent.

What to do next

  1. Review grant funding strategies in light of the MBRS program termination
  2. Ensure all future grant applications and research support initiatives comply with current legal standards regarding race and ethnicity

Source document (simplified)

Content

ACTION:

Final rule.

SUMMARY:

The Department of Health and Human Services (HHS), in consultation with the National Institutes of Health (NIH), is repealing
the regulation relating to the Minority Biomedical Research Support (MBRS) program in compliance with Executive Order (E.O.)
14173 (Ending Illegal Discrimination and Restoring Merit-Based Opportunity) and E.O. 14151 (Ending Radical and Wasteful Government DEI Programs and Preferencing), and to abide by Supreme Court precedent. HHS remains committed to ensuring equal treatment under the law throughout its
grant programs.

DATES:

This final rule is effective September 25, 2025.

FOR FURTHER INFORMATION CONTACT:

Matthew Zorn, Deputy General Counsel, U.S. Department of Health and Human Services, Office of the General Counsel, 200 Independence
Avenue SW, Washington, DC 20201. Telephone:

     (202) 795-7645. Email: *Matthew.Zorn@hhs.gov.*

SUPPLEMENTARY INFORMATION:

I. General Discussion

The MBRS program prioritizes racial classifications in awarding federal funding. The stated goal of the program is to “increase
the numbers of ethnic minority faculty, students, and investigators engaged in biomedical research and to broaden the opportunities
for participants in biomedical research of ethnic minority faculty, students, and investigators” (1) and relies on “minority student enrollment” to determine applicant eligibility. (2)

The regulation and the MBRS program generally are contrary to the Supreme Court's decision in Students for Fair Admissions, Inc. v. President and Fellows of Harvard College, (3) which held that race-based affirmative action in college admissions violates the Equal Protection Clause of the 14th Amendment
and Title VI of the Civil Rights Act of 1964. The goal of promoting diversity, even if commendable, cannot survive review
under equal protection principles. (4)

The principles identified in Students for Fair Admissions also apply to the federal government (5) and require repeal of the MBRS program. Therefore, HHS is repealing the regulation codified at 42 CFR 52c and terminating
the MBRS program.

II. Procedural Issues

Under 5 U.S.C. 553(b)(3)(B), an agency may dispense with the notice-and-comment procedures when it finds the notice-and-comment
to be “impractical, unnecessary, or contrary to the public interest.” Because the MBRS regulations are contrary to Supreme
Court precedent on their face, the NIH finds good cause that notice-and-comment on this final rule is impractical, unnecessary,
and contrary to the public interest.

This final rule has been determined to be exempt from review for purposes of E.O. 12866.

This rule does not impose information collection and recordkeeping requirements and therefore does not need to be reviewed
by the Office of Management and Budget under the Paperwork Reduction Act of 1995.

List of Subjects in 42 CFR Part 52c

Educational study programs, Grant programs—health, Medical research, Reporting and recordkeeping requirements.

PART 52c—[REMOVED AND RESERVED]

Regulatory Text For the reasons stated in the preamble, under the authority of 42 U.S.C. 241, HHS amends Subchapter D of Chapter I of Title
42 of the Code of Federal Regulations by removing part 52c.

Robert F. Kennedy, Jr., Secretary, U.S. Department of Health and Human Services. [FR Doc. 2025-16321 Filed 8-25-25; 8:45 am] BILLING CODE 4140-01-P

Footnotes

(1) Part 52c—Minority Biomedical Research Support Program, 45 FR 12,246 (Feb. 25, 1980).

(2) 42 CFR 52c.3(a).

(3) 600 U.S. 181 (2023).

(4) Id. at 214.

(5) See Fullilove v. Klutznick, 448 U.S. 448, 480 (1980).

Download File

Download

Classification

Agency
NIH
Published
September 25th, 2025
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Substantive

Who this affects

Applies to
Educational institutions Healthcare providers
Geographic scope
National (US)

Taxonomy

Primary area
Healthcare
Operational domain
Compliance
Topics
Civil Rights Education

Get Healthcare alerts

Weekly digest. AI-summarized, no noise.

Free. Unsubscribe anytime.

Get alerts for this source

We'll email you when Regs.gov: National Institutes of Health publishes new changes.

Free. Unsubscribe anytime.