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In vivo imaging apparatus, systems, and methods using optical nanoparticles

Favicon for changeflow.com USPTO Patent Grants - Diagnosis & Surgery (A61B)
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Summary

The USPTO has granted patent US12582302B2 to The Regents of the University of California for in vivo imaging apparatus, systems, and methods using optical nanoparticles. The patent covers techniques for illuminating and imaging tissues, such as cancer tissues, using upconverting nanoparticles to improve resolution and reduce imager size.

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What changed

The United States Patent and Trademark Office (USPTO) has issued patent US12582302B2, titled "In vivo imaging apparatus, systems, and methods using optical nanoparticles." The patent, assigned to The Regents of the University of California, details the use of optical nanoparticles, specifically upconverting nanoparticles, for improved in vivo tissue imaging, including cancer tissues. The technology involves introducing nanoparticles into a patient, illuminating them at a specific wavelength, and then imaging at a different wavelength to enhance resolution and potentially decrease the size of imaging devices.

This patent grant represents a new intellectual property right for a specific technology in medical imaging. While it does not impose direct compliance obligations on other entities, it may impact future product development and market entry for companies operating in the medical device and diagnostic imaging sectors. Companies developing or utilizing similar in vivo imaging technologies should review the patent claims to ensure they do not infringe on this granted patent. The filing date for this application was September 4, 2020.

Archived snapshot

Mar 27, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Apparatus, systems and methods for in vivo imaging

Grant US12582302B2 Kind: B2 Mar 24, 2026

Assignee

The Regents of the University of California

Inventors

Moshiur M. Anwar, Catherine Park, Bernhard Boser

Abstract

The disclosed apparatus, systems and methods relate to the use of optical nanoparticles in the illumination and imaging of tissues such as cancer tissues. Optical nanoparticles such as upconverting nanoparticles can be introduced into a patient and illuminated at a first time and wavelength and then imaged at a second time and wavelength to improve resolution and reduce imager size.

CPC Classifications

A61B 1/05 A61B 1/00009 A61B 1/000094 A61B 1/043 A61B 1/0684 A61B 1/3132 A61B 5/0091 A61B 2560/0418 A61B 1/0676 A61B 5/0071 A61B 5/0077 A61B 5/0084 A61B 5/0086 A61B 5/6848 A61B 10/0041

Filing Date

2020-09-04

Application No.

17639722

Claims

26

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Last updated

Classification

Agency
USPTO
Published
March 24th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12582302B2

Who this affects

Applies to
Drug manufacturers Medical device makers Healthcare providers
Industry sector
3345 Medical Device Manufacturing 3254 Pharmaceutical Manufacturing
Activity scope
Medical Imaging Drug Delivery
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Research & Development
Topics
Medical Devices Pharmaceuticals

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