Cryogenic Applicator Patent for Skin Treatment

ChangeBridge: Patent Grants - Diagnosis & Surgery (A61B)

Published April 7th, 2026

Detected April 8th, 2026

Summary

The USPTO granted Patent US12594112B2 to Cryogeneus Inc. on April 7, 2026, covering a portable cryogenic applicator system for skin treatment. The patent claims a vessel for liquid nitrogen delivery through a porous biocompatible rotating roller, a capillary U-bend preventing spontaneous discharge, and a vacuum valve maintaining ambient external surface temperature. The patent includes 19 claims covering the cryogenic applicator design and operation for dermatological applications.

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What changed

USPTO issued Patent US12594112B2 to Cryogeneus Inc. covering a portable cryogenic applicator for skin treatment using liquid nitrogen delivered through a porous biocompatible rotating roller. The patent includes a capillary U-bend to prevent spontaneous discharge during filling and a vacuum valve creating an insulating vacuum environment to maintain ambient external temperature. Control valves regulate working pressure for controlled liquid nitrogen delivery to patient skin surfaces.

Manufacturers developing cryogenic dermatological devices should review this patent to ensure their products do not infringe the 19 granted claims. Healthcare providers utilizing cryogenic skin treatments may see limited market options or licensing requirements depending on Cryogeneus's enforcement approach.

What to do next

Monitor for patent validity challenges
Review product development plans for potential infringement

Source document (simplified)

← USPTO Patent Grants

Cryogenic applicator

Grant US12594112B2 Kind: B2 Apr 07, 2026

Assignee

Cryogeneus Inc.

Inventors

Olga Goulko, Khasanbi Erganokov, Valentin Pavlov

Abstract

A portable cryogenic applicator includes a vessel for liquid nitrogen to deliver liquid nitrogen for treatment of skin surfaces using the rotating roller from porous biocompatible material. The cryogenic applicator includes a capillary U-bend to prevent spontaneous discharge of liquid nitrogen through the capillary system to the roller during filling or refilling the cryogenic applicator with liquid nitrogen. The cryogenic applicator also includes a vacuum valve that produce an insulating vacuum environment in a vacuum cavity to prevent heat transfer between the vessel for liquid nitrogen and a vacuum casing, which allows the external surface of the cryogenic applicator to be maintained at ambient temperature. The cryogenic applicator may include a control valve for regulating and maintaining the working pressure in the vessel for liquid nitrogen sufficient to deliver liquid nitrogen through the capillary system and the porous roller body to the surface skin of a patient.

CPC Classifications

A61B 18/02 A61B 2018/0262 A61B 18/0218 A61B 2018/00041 A61B 2018/0212 A61B 2018/00101 A61B 2018/0275 A61B 2017/00084 A61B 2018/00095 A61B 2018/00166 A61B 2018/0293 A61B 2218/002 F17C 2221/014 F17C 2223/0161 F17C 2270/02 F17C 2201/032 F17C 2201/058 F17C 2205/0332 F17C 2205/0382 F17C 2223/047 F17C 2270/0509 F17C 9/00 F17C 2203/0629 F17C 2225/0161 F25D 3/10 F25D 3/107 F04C 2270/0421 A45D 34/04 B65D 83/285