Immersive Virtual Reality and Exercise Programs in Multiple Sclerosis (NCT07543900)
Summary
ClinicalTrials.gov registered study NCT07543900 titled 'Immersive Virtual Reality and Exercise Programs in Multiple Sclerosis' evaluating virtual exercise-based interventions for patients with multiple sclerosis (MS). The study identifies conditions including Multiple Sclerosis, Exercise, Physical Therapy, Virtual Reality Exposure Therapy, and Rehabilitation Exercise. MS is described as a chronic neuroimmunological and degenerative disease and one of the leading causes of non-traumatic disability in young adults, with considerable healthcare burden. The trial is part of the ExeRVIEM II project examining high-intensity exercise programs with immersive VR.
“Multiple sclerosis (MS) is a chronic neuroimmunological and degenerative disease characterized by demyelination within the central nervous system.”
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What changed
This ClinicalTrials.gov record registers a clinical study (NCT07543900) examining immersive virtual reality combined with exercise programs as an intervention for multiple sclerosis patients. The study lists conditions including MS, Exercise, Physical Therapy, and Virtual Reality Exposure Therapy, with a virtual exercise-based program as the primary intervention. The record notes that therapeutic exercise has evolved from being potentially harmful to recognized as a safe and effective intervention for MS, capable of improving gait, balance, cardiorespiratory fitness, fatigue, and quality of life.
Healthcare providers and clinical investigators conducting MS rehabilitation research may find this trial relevant to understanding current approaches to VR-based exercise interventions. The ExeRVIEM II project referenced aligns with systematic review evidence showing structured exercise (including supervised high-intensity protocols) is safe and can improve functional outcomes in MS patients.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Immersive Virtual Reality and Exercise Programs in Multiple Sclerosis
N/A NCT07543900 Kind: NA Apr 22, 2026
Abstract
TITLE: Immersive Virtual Reality and Exercise Programs in Multiple Sclerosis
INTRODUCTION: Multiple sclerosis (MS) is a chronic neuroimmunological and degenerative disease characterized by demyelination within the central nervous system. Its clinical course involves motor impairment, sensory disturbances, cognitive dysfunction, and a progressive decline in functional independence. MS is one of the leading causes of non-traumatic disability in young adults. This highlights the considerable impact of the disease, both in terms of healthcare burden and healthcare expenditure. Within this context, therapeutic exercise has evolved from being considered potentially harmful to being recognized as a safe and effective intervention capable of improving gait, balance, cardiorespiratory fitness, fatigue, and quality of life in people with MS. A model has been proposed for prescribing and progressing exercise at different stages of MS: passive range-of-motion exercises designed for patients with the most severe symptoms, a second stage incorporating active muscle-strengthening exercises, and finally, integrated exercise programs that incorporate strength, endurance, balance, and coordination training. Evidence from systematic reviews and meta-analyses shows that structured exercise (including high-intensity protocols when performed under supervision) is safe and can improve functional outcomes. Our ExeRVIEM II project (High-Intensity Exercise Program with Immersive Virtual Reality in...
Conditions: Multiple Sclerosis, Exercise (EX), Physical Therapy, Virtual Reality Exposure Therapy, Rehabilitation Exercise
Interventions: Virtual exercise based program
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