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Vibratory Anesthesia on Pain Following Corticosteroid Injections

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Summary

NCT07553273 is a clinical trial registration on ClinicalTrials.gov evaluating injectional pain at the site of needle insertion for corticosteroid injections of the upper extremity. The study compares three anesthesia modes: control (no anesthesia), vibrational anesthesia using the Digivibe Device, and vapo-coolant anesthesia. Participants with bilateral arthritis of the wrist, hands, tendinopathy, arthropathy, or compression neuropathy will be enrolled to determine which method is associated with the least pain. The trial was registered with a last updated date of April 27, 2026.

“This research study aims to evaluate injectional pain at the site of needle insertion for corticosteroid injections (CSI) of the upper extremity depending on different modes of anesthetics.”

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About this source

ClinicalTrials.gov is the NIH-run registry of every clinical trial conducted in the United States, plus most international trials sponsored by US-based companies or institutions. By federal law, sponsors must register Phase 2 through Phase 4 studies before enrolling patients and post results within a year of completion. This feed tracks every new trial registration and study update, around 700 a month: drug interventions, device studies, behavioral protocols, observational research. Watch this if you scout drug candidates moving into mid or late-stage development, monitor competitor pipelines, or follow rare disease research where new trials signal patient hope. GovPing parses sponsor, phase, intervention, and target indication on each entry.

What changed

This document registers a clinical trial on ClinicalTrials.gov under NIH authority. The study will evaluate pain perception during corticosteroid injections of the upper extremity across three anesthesia conditions: control (no anesthesia), vibrational anesthesia using the Digivibe Device, and vapo-coolant anesthesia. Participants include individuals with bilateral arthritis of the wrist, bilateral arthritis of hands, tendinopathy, arthropathy, and compression neuropathy.

For healthcare providers and clinical investigators, this trial represents an emerging approach to reducing procedural pain in musculoskeletal care. The use of vibrational anesthesia as an intervention modality may be relevant for orthopedic practices, pain management clinics, and physical medicine departments performing corticosteroid injections. Sponsors considering similar pain-management trial designs may find the comparison methodology of interest.

Archived snapshot

Apr 27, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

Vibratory Anesthesia on Pain Following Corticosteroid Injections

N/A NCT07553273 Kind: NA Apr 27, 2026

Abstract

This research study aims to evaluate injectional pain at the site of needle insertion for corticosteroid injections (CSI) of the upper extremity depending on different modes of anesthetics. Each individual's perception of pain upon receiving a CSI with two out of three modes of anesthesia (control/no anesthesia, vibrational anesthesia, vapo-coolant anesthesia) will be utilized to compare these variables and determine the method that is associated with the least pain.

Conditions: Bilateral Arthritis of Wrist, Tendinopathy, Arthropathy, Compression Neuropathy, Bilateral Arthritis of Hands

Interventions: Digivibe Device

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Classification

Agency
NIH
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Docket
NCT07553273

Who this affects

Applies to
Healthcare providers Clinical investigators
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Pain management research Anesthesia device evaluation
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Pharmaceuticals Public Health

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