Observational Study on Pleasant Touch in Chronic Pain
Summary
NIH has registered a new observational study (NCT07551687) examining pleasant touch perception in individuals with chronic pain and its association with central sensitization and interoceptive awareness. Participants will be recruited from a specialist Pain Clinic in Västra Götaland, Sweden, and will complete online questionnaires assessing pain, touch experience, interoceptive awareness, and central sensitization. The study aims to compare pleasant touch perception across different pain mechanism types: nociceptive, neuropathic, and nociplastic.
“The goal of this observational study is to learn how individuals with chronic pain experience pleasant touch and how often they are exposed to such touch in their daily lives.”
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What changed
NIH has registered a new observational clinical trial on ClinicalTrials.gov. The study will investigate how individuals with chronic pain perceive pleasant touch and its relationship to central sensitization, interoceptive awareness, and body awareness. Participants referred to a specialist Pain Clinic in Västra Götaland will complete online questionnaires and provide clinical data. The study compares three dominant pain mechanism groups: nociceptive, neuropathic, and nociplastic.
This study registration does not create compliance obligations for any regulated entities. Healthcare researchers studying pain mechanisms may find this study relevant for identifying current research approaches in the field of chronic pain phenotypes.
Archived snapshot
Apr 28, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Pleasant Touch Perception in Persistent Pain.
Observational NCT07551687 Kind: OBSERVATIONAL Apr 27, 2026
Abstract
The goal of this observational study is to learn how individuals with chronic pain experience pleasant touch and how often they are exposed to such touch in their daily lives. The study also aims to examine how these experiences relate to pain sensitivity and body awareness. The main questions it aims to answer are:
How is the perception of pleasant touch associated with central sensitization and interoceptive awareness in individuals with chronic pain?
Does the perception of pleasant touch differ between individuals with different dominant pain mechanisms (nociceptive, neuropathic, and nociplastic)?
Participants referred to a specialist Pain Clinic in Västra Götaland as part of their regular care will be invited to take part. Those who consent will complete online questionnaires assessing pain, experience and exposure to touch, interoceptive awareness, and central sensitization. Clinical data such as pain diagnosis and medical history will also be collected.
Conditions: Chronic Pain, Persistent Pain
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