Ventus Therapeutics Patent, cGAS Inhibitors, Apr 23
Summary
Ventus Therapeutics Patent, cGAS Inhibitors, Apr 23
About this source
USPTO classification C07D covers heterocyclic organic compounds: the chemical core of most small-molecule drugs, including kinase inhibitors, GLP-1 receptor agonists, antibiotics, antivirals, and CNS therapies. Every newly published application in C07D lands in this feed, around 160 a month. Applications publish 18 months after filing, so this feed reveals what medicinal chemistry groups at Pfizer, Novartis, Roche, Shionogi, and others were synthesizing in the prior year and a half. Watch this if you run a medicinal chemistry program, file patent clearance for new drug candidates, scout competitor pipelines before clinical readouts, or track heterocyclic innovation across therapeutic areas.
Archived snapshot
Apr 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
6-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF
Application US20260108509A1 Kind: A1 Apr 23, 2026
Assignee
Ventus Therapeutics U.S., Inc.
Inventors
Patrick Cyr, Ramsay Beveridge, Nathan Scott Abraham, Yann Lamotte, Audrey Dumoulin
Abstract
The present disclosure relates to compounds of Formula (I) and (II): and pharmaceutically acceptable salts and/or isotopically labeled derivatives thereof, wherein X1, X2, RA, y, R3, R4, R5, R6, R7, a and b are as defined herein, and Ring A2 is a 6-membered heteroaryl ring, and methods of preparation of same. The present disclosure further relates to pharmaceutical compositions and methods of treatment, e.g., of cGAS-related diseases and disorders, comprising compounds of Formula (I). Compounds of Formula (II) may be useful as tool compounds in binding, functional, and/or cellular assays.
CPC Classifications
A61K 31/4985 C07D 471/14 C07D 491/22
Filing Date
2025-10-17
Application No.
19362283
Related changes
Get daily alerts for USPTO Patent Applications - Organic Chemistry (C07D)
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from USPTO.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Browse Categories
Get alerts for this source
We'll email you when USPTO Patent Applications - Organic Chemistry (C07D) publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.