Temporal Interference Stimulation, Early Alzheimer's, 40 Participants

NIH registered a new clinical trial (NCT07543094) on ClinicalTrials.gov investigating the efficacy and safety of Temporal Interference Stimulation (TIS) for cognitive function in early-stage Alzheimer's disease. The study will enroll 40 participants randomized to active TIS or sham stimulation over a 2-week period, with assessments at baseline, post-treatment, and 12 weeks after treatment.

Affected parties include clinical investigators conducting Alzheimer's disease research, patients meeting early-stage Alzheimer's criteria, and sponsors of neuromodulation device studies. ClinicalTrials.gov registration is mandatory for applicable trials under FDA regulations — sponsors and investigators should confirm registration status and ensure trial information is current and accurate.