Substituted Indole Compounds With Inhibitory Activity for Treating Acute Renal Failure
Summary
USPTO granted patent US12606557B2 to the University of Pittsburgh-of the Commonwealth System of Higher Education on April 21, 2026. The patent covers substituted indole compounds and compositions for treating or preventing acute renal failure, as well as infectious diseases and cancer. The application (No. 17927406) was filed on May 27, 2021, with 17 claims and CPC classification C07D 471/04.
What changed
USPTO issued patent US12606557B2 to the University of Pittsburgh, conferring exclusive rights to substituted indole compounds and compositions for therapeutic use. The patent lists five inventors and covers methods of treating acute renal failure, infectious diseases, and cancer using the claimed compounds.
Pharmaceutical and biotechnology companies developing treatments for renal disease, infectious diseases, or oncology should monitor this intellectual property landscape. The patent may affect freedom-to-operate analyses for related therapeutic programs, and companies with competing or complementary indole-based compounds should evaluate potential licensing or design-around strategies.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Substituted indoles with inhibitory activity
Grant US12606557B2 Kind: B2 Apr 21, 2026
Assignee
UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
Inventors
Donna Huryn, Neil Hukriede, Keith Long, Jagannath Panda, Sipak Joyasawal
Abstract
Disclosed are substituted indole compounds and compositions. The substituted indole compounds and compositions can be used for treating or preventing acute renal failure in a subject. The compounds and compositions can also be used for treating an infectious disease or cancer.
CPC Classifications
C07D 471/04
Filing Date
2021-05-27
Application No.
17927406
Claims
17
Mentioned entities
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