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Siponimod and Beta-Blocker Combination for Treating Autoimmune Disease

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Summary

The USPTO published application US20260108490A1, a method-of-treatment patent covering siponimod in combination with a beta-blocker for treating autoimmune diseases, filed on December 22, 2025. The application names 11 inventors and classifies the invention under CPC categories including A61K (medicinal preparations) and A61P 37/00 (immunoregulating agents). Pharmaceutical companies developing autoimmune disease therapies should review freedom-to-operate positions regarding S1P receptor modulators combined with cardiovascular agents.

“The present invention relates to methods of treating autoimmune diseases with siponimod in patients receiving additionally a beta-blocker.”

USPTO , verbatim from source
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About this source

GovPing monitors USPTO Patent Applications - Therapeutics (A61P) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 211 changes logged to date.

What changed

The USPTO published patent application US20260108490A1 for a method of treating autoimmune diseases using siponimod in patients who are additionally receiving a beta-blocker. The application, filed December 22, 2025, names 11 inventors and classifies the invention under therapeutic composition categories A61K and immunoregulating category A61P 37/00.

Pharmaceutical and biotech companies engaged in autoimmune disease drug development should assess potential freedom-to-operate implications arising from this patent filing, particularly regarding S1P receptor modulator and cardiovascular drug combination approaches. Researchers investigating siponimod combination therapies and competitive programs in the autoimmune space should factor this IP publication into their development and patent strategies.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

TREATMENT OF AUTOIMMUNE DISEASE IN A PATIENT RECEIVING ADDITIONALLY A BETA-BLOCKER

Application US20260108490A1 Kind: A1 Apr 23, 2026

Inventors

Vassilios Aslanis, Shibadas Biswal, Alan John Camm, Pierre Jordaan, Eric Legangneux, Parasar Pal, Atul Keshav Pawar, Florine Polus, Alexandros Sagkriotis, Kasra Shakeri-Nejad, Uday Kiran Veldandi

Abstract

The present invention relates to methods of treating autoimmune diseases with siponimod in patients receiving additionally a beta-blocker.

CPC Classifications

A61K 31/397 A61K 9/2018 A61K 31/138 A61K 45/06 A61P 37/00

Filing Date

2025-12-22

Application No.

19428890

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Last updated

Classification

Agency
USPTO
Published
April 23rd, 2026
Instrument
Rule
Branch
Executive
Legal weight
Binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent filing Pharmaceutical research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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