USPTO Patent Application: RNA Complexes for Cancer Metastasis Treatment
Summary
The USPTO has published a new patent application detailing RNA complexes and nanostructures for cancer metastasis treatment. The application describes a one-step CMC production method for RNA therapeutic complexes containing nucleoside analogues, which self-assemble during RNA synthesis.
What changed
This document is a USPTO patent application (US20260083770A1) filed on September 28, 2023, concerning novel RNA complexes and nanostructures for treating cancer metastasis. The invention focuses on a simplified, one-step CMC production process for RNA therapeutic complexes that incorporate nucleoside analogues, allowing for self-assembly during RNA synthesis without additional conjugation steps.
As this is a patent application, it does not impose direct regulatory obligations or compliance deadlines on regulated entities. However, it signifies potential future developments in pharmaceutical and biotechnology research. Companies in the pharmaceutical and medical device sectors involved in oncology treatments should be aware of this technological advancement for competitive intelligence and potential licensing opportunities.
Archived snapshot
Mar 26, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
RNA COMPLEXES AND NANOSTRUCTURES FOR TREATMENT OF CANCER METASTASIS
Application US20260083770A1 Kind: A1 Mar 26, 2026
Inventors
Peixuan GUO, Xin LI, Daniel BINZEL, Kai JIN
Abstract
Disclosed herein are compositions and methods for one step CMC production of RNA therapeutic complexes (nanostructures) that contain nucleoside analogues. In some embodiments, the nucleoside analogues are incorporated into RNA oligonucleotides that self-assemble into an RNA complex during RNA synthesis in a one-step production. Therefore, no additional conjugation or synthesis processes are required.
CPC Classifications
A61K 31/7105 A61K 31/7115 A61K 31/713 A61K 47/549 A61K 47/6929 A61P 35/04 C12N 15/1135 C12N 2310/11 C12N 2310/335
Filing Date
2023-09-28
Application No.
19110315
Named provisions
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