RNA COMPLEXES AND NANOSTRUCTURES FOR TREATMENT OF CANCER METASTASIS

Abstract

Disclosed herein are compositions and methods for one step CMC production of RNA therapeutic complexes (nanostructures) that contain nucleoside analogues. In some embodiments, the nucleoside analogues are incorporated into RNA oligonucleotides that self-assemble into an RNA complex during RNA synthesis in a one-step production. Therefore, no additional conjugation or synthesis processes are required.

CPC Classifications