Phage-Derived Particles Deliver DNA Into C. Acnes, Eligo Bioscience
Summary
USPTO published patent application US20260109991A1 by Eligo Bioscience on April 23, 2026, covering phage-derived particles for delivering DNA payloads into Cutibacterium acnes bacteria. The application, filed October 24, 2025, discloses engineered vectors with C. acnes phage packaging signals and genes of interest, along with producer cells, phage-derived particles, and methods for transducing C. acnes with transgenes. Inventors include Aymeric LEVEAU, Ines CANADAS BLASCO, Aurelie MATHIEU, and Antoine DECRULLE.
“The invention relates to C. acnes carrying DNA vectors with a C. acnes phage packaging signal and a gene of interest.”
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GovPing monitors USPTO Patent Applications - Biotech (C12N) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 199 changes logged to date.
What changed
USPTO published Eligo Bioscience's patent application covering engineered C. acnes phage-derived particles capable of robustly transducing C. acnes receiver cells with genes of interest. The application discloses vectors with C. acnes phage packaging signals, producer cells carrying these vectors, and methods for transgene expression in modified C. acnes.
Affected parties include developers of microbiome therapeutics, dermatological treatments, and synthetic biology applications involving Cutibacterium acnes. Biotech and pharmaceutical companies working on phage therapy platforms or acne treatments should monitor this application's prosecution for potential freedom-to-operate implications.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
PHAGE-DERIVED PARTICLES FOR IN SITU DELIVERY OF DNA PAYLOAD INTO C. ACNES POPULATION
Application US20260109991A1 Kind: A1 Apr 23, 2026
Assignee
Eligo Bioscience
Inventors
Aymeric LEVEAU, Ines CANADAS BLASCO, Aurelie MATHIEU, Antoine DECRULLE
Abstract
The invention relates to C. acnes carrying DNA vectors with a C. acnes phage packaging signal and a gene of interest. The invention encompasses a C. acnes producer cell carrying DNA vectors, with a C. acnes phage packaging signal and a gene of interest, for the production of phage-derived particles that can robustly transduce C. acnes receiver cell allowing transgene expression. The invention encompasses C. acnes phage-derived particles carrying these vectors, C. acnes containing these vectors or modified by transduction of these phage-derived particles, and methods of using these phage-derived particles.
CPC Classifications
C12N 15/76 A61K 39/02 A61K 39/05 A61P 17/10 C12N 9/22 C12N 15/11 A61K 2039/53 C12N 9/64 C12N 2310/20 C12N 2795/10343 C12N 2800/101 C12N 2800/80
Filing Date
2025-10-24
Application No.
19368024
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