Peri-implantitis Surgery Trial Compares Two Methods
Summary
This ClinicalTrials.gov registry entry documents an interventional randomized study comparing two surgical approaches for treating peri-implantitis in dental implant patients. The trial will enroll participants and randomly assign them to receive either resective surgery with implantoplasty or resective surgery with mechanical debridement alone. Participants will undergo blood sampling at multiple timepoints, provide gum tissue and peri-implant fluid samples at baseline and 3 months, and be followed in a 5-year maintenance program. The trial is registered as NCT07550127.
About this source
ClinicalTrials.gov is the NIH-run registry of every clinical trial conducted in the United States, plus most international trials sponsored by US-based companies or institutions. By federal law, sponsors must register Phase 2 through Phase 4 studies before enrolling patients and post results within a year of completion. This feed tracks every new trial registration and study update, around 700 a month: drug interventions, device studies, behavioral protocols, observational research. Watch this if you scout drug candidates moving into mid or late-stage development, monitor competitor pipelines, or follow rare disease research where new trials signal patient hope. GovPing parses sponsor, phase, intervention, and target indication on each entry.
What changed
This ClinicalTrials.gov registry entry records a randomized clinical trial comparing two surgical treatments for peri-implantitis around dental implants. The study compares resective surgery with implantoplasty against resective surgery with mechanical debridement alone. Participants will provide blood samples before surgery, at 48 hours and 2 weeks post-surgery, plus tissue and fluid samples at baseline and 3 months. The 5-year follow-up maintenance program will track long-term outcomes. The document serves as a study registration record and does not impose any regulatory requirements or compliance obligations.
Archived snapshot
Apr 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Peri-implantitis Management: Surgical and Maintenance Outcomes
N/A NCT07550127 Kind: NA Apr 24, 2026
Abstract
The goal of this clinical trial is to learn how two standard surgical treatments for peri-implantitis affect inflammation around dental implants. Participants will be randomly assigned to receive resective surgery with implantoplasty or resective surgery with mechanical debridement only. Participants will provide blood samples before surgery, about 48 hours and 2 weeks after surgery. Participants will also provide a small gum tissue sample and fluid from around the implant at baseline and about 3 months after surgery. Participants will be followed in a maintenance program for up to 5 years.
Conditions: Peri-implantitis
Interventions: Resective surgery with implantoplasty, Resective surgery with mechanical debridement
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