NCT07546903: SIFI vs QIPB Nerve Block Hip Fracture Surgery Study
Summary
A new observational clinical trial (NCT07546903) registered on April 23, 2026, will directly compare the postoperative analgesic efficacy of Suprainguinal Fascia Iliaca Block (SIFI) and Quadro-Iliac Plane Block (QIPB) in patients undergoing hip fracture surgery. The study addresses a gap in the literature, as no prior head-to-head comparison of these two nerve block techniques exists, despite both being shown to reduce opioid consumption. The trial will enrol patients receiving either intervention for hip fracture repair.
“Although opioids are traditionally used for postoperative pain management, their adverse effects have led to increased interest in multimodal analgesia, particularly peripheral nerve blocks.”
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What changed
A new observational clinical trial (NCT07546903) titled "Comparison of Analgesic Efficacy of Suprainguinal Fascia Iliaca and Quadro-iliac Blocks in Hip Fracture Surgery" was registered on April 23, 2026. The study will enrol patients undergoing hip fracture surgery and randomly assign them to receive either Suprainguinal Fascia Iliaca Block (SIFI) or Quadro-Iliac Plane Block (QIPB) for postoperative analgesia, measuring opioid consumption and pain scores as primary outcomes.
Healthcare providers, clinical investigators, and researchers involved in perioperative pain management for orthopaedic trauma should note this trial fills an evidence gap: while both techniques independently demonstrate analgesic efficacy and opioid-sparing effects, no published study has directly compared them. Investigators conducting related research in fascia iliaca blocks or geriatric orthopaedic analgesia may wish to monitor the study's outcomes for inclusion in systematic reviews or clinical practice guidelines.
Archived snapshot
Apr 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Comparison of Analgesic Efficacy of Suprainguinal Fascia Iliaca and Quadro-iliac Blocks in Hip Fracture Surgery
Observational NCT07546903 Kind: OBSERVATIONAL Apr 23, 2026
Abstract
Hip fractures are common in the elderly and are associated with significant morbidity and mortality. Effective early analgesia is crucial for facilitating mobilization, reducing pulmonary complications, and improving overall outcomes. Although opioids are traditionally used for postoperative pain management, their adverse effects have led to increased interest in multimodal analgesia, particularly peripheral nerve blocks.
The suprainguinal fascia iliaca block (SIFI) is a modified technique that allows wider spread of local anesthetic, providing more effective blockade of the femoral, obturator, and lateral femoral cutaneous nerves. The quadro-iliac plane block (QIPB), a recently described interfascial block, is performed at the level of the anterior superior iliac spine and may also affect branches of the lumbar and sacral plexus.
While both techniques have been shown to provide effective analgesia and reduce opioid consumption, there is no study directly comparing them. Therefore, this study aims to compare the postoperative analgesic efficacy of SIFI and QIPB in patients undergoing hip fracture surgery.
Conditions: Post Operative Pain
Interventions: Suprainguinal Fascia Iliaca Block, Quadro-Iliac Plane Block
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