PEEP Titration Effects on VExUS and Renal Outcomes in ARDS Patients
Summary
A prospective observational cohort study has been registered on ClinicalTrials.gov (NCT07545252) to evaluate the effect of different levels of PEEP titration on VExUS score and renal outcomes in 40 patients diagnosed with Acute Respiratory Distress Syndrome. The study uses VExUS score as the intervention and observational endpoint, with an anticipated enrollment of 40 participants. This registry entry documents the study design, condition, and interventions without imposing any compliance obligation.
“This study is a prospective observational cohort study conducted planned to include 40 patients with ARDS to assess the effect of different levels of PEEP titration on VExUS score and renal outcomes in patients with Acute Respiratory Distress Syndrome.”
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What changed
A new prospective observational cohort study (NCT07545252) has been registered on ClinicalTrials.gov, designed to enroll 40 patients with Acute Respiratory Distress Syndrome to assess how different levels of positive end-expiratory pressure titration affect the Venous Excess Ultrasound Score and downstream renal outcomes. The study uses VExUS score as both an intervention and an observational measure, with no therapeutic drug or device under investigation. The primary condition under study is ARDS, a severe form of respiratory failure with significant mortality risk.
Affected parties include clinical investigators and healthcare institutions conducting or sponsoring critical care research. As a registry entry rather than an interventional regulatory action, this document imposes no immediate compliance obligations, but study sponsors and institutional review boards should note the trial's parameters when reviewing concurrent or competing ARDS-intervention studies. The registration reflects adherence to federal clinical trial reporting requirements under applicable NIH policies.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Effect of Positive End-Expiratory Pressure Titration on Venous Excess Ultrasound Score and Renal Outcomes in Patients With Acute Respiratory Distress Syndrome
Observational NCT07545252 Kind: OBSERVATIONAL Apr 22, 2026
Abstract
This study is a prospective observational cohort study conducted planned to include 40 patients with ARDS to assess the effect of different levels of PEEP titration on VExUS score and renal outcomes in patients with Acute Respiratory Distress Syndrome.
Conditions: Acute Respiratory Distress Syndrome (ARDS)
Interventions: VExUS score
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