Serum Electrolytes and Contrast-Induced Nephropathy in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment
ClinicalTrials.gov Studies
Summary
A new observational cohort study (NCT07546448) has been registered on ClinicalTrials.gov, examining the relationship between serum electrolyte levels and contrast-induced acute kidney injury (CI-AKI) in patients with acute ischemic stroke undergoing endovascular therapy (EVT). The retrospective study will analyze patients treated between 2018 and 2026, classifying participants based on the presence or absence of CI-AKI per serum creatinine changes, with secondary objectives including 90-day mortality and dialysis dependency evaluation.
“In this retrospective cohort study, patients treated with EVT between 2018 and 2026 will be analyzed.”
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What changed
A new clinical trial registration (NCT07546448) titled 'Serum Electrolytes and Contrast-Induced Nephropathy in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment' has been added to the NIH ClinicalTrials.gov registry. The observational cohort study will retrospectively analyze patients treated with endovascular therapy between 2018 and 2026, classifying subjects by the presence or absence of contrast-induced acute kidney injury based on serum creatinine changes.
Affected parties include clinical investigators and healthcare institutions involved in stroke and endovascular care, as well as public health authorities tracking acute kidney injury outcomes. The study's primary objective is to determine whether serum electrolyte imbalances are associated with CI-AKI risk; secondary endpoints include 90-day mortality and dialysis dependency rates. No new compliance obligations are imposed on any party.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Serum Electrolytes and Contrast-Induced Nephropathy in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment
Observational NCT07546448 Kind: OBSERVATIONAL Apr 22, 2026
Abstract
This study aims to evaluate the relationship between serum electrolyte levels and the development of contrast-induced acute kidney injury (CI-AKI) in patients with acute ischemic stroke undergoing endovascular therapy (EVT).
Contrast-induced nephropathy remains a significant complication associated with endovascular procedures and is linked to increased morbidity and mortality. While several risk factors have been identified, the role of serum electrolyte imbalances in the development of CI-AKI has not been fully elucidated.
In this retrospective cohort study, patients treated with EVT between 2018 and 2026 will be analyzed. Patients will be classified based on the presence or absence of CI-AKI according to changes in serum creatinine levels. Demographic data, comorbidities, laboratory parameters-including serum electrolytes-and procedural variables will be compared between groups.
The primary objective is to determine whether serum electrolyte levels are associated with the risk of CI-AKI. Secondary objectives include evaluating 90-day mortality and dialysis dependency in patients who develop CI-AKI.
Conditions: Acute Ischemic Stroke, Contrast-induced Nephropathy, Acute Kidney Injury
Interventions: No intervention (observational cohort study)
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