PCV-VG Versus VCV Ventilation Modes in Laparoscopic Abdominal Cancer Surgeries
ClinicalTrials.gov Studies
Summary
A randomized clinical trial (NCT07550738) registered with ClinicalTrials.gov will compare two mechanical ventilation modes—Pressure-Controlled Volume Guaranteed (PCV-VG) versus Volume-Controlled Ventilation (VCV)—in patients undergoing laparoscopic abdominal cancer surgeries with exaggerated Trendelenburg positioning. The primary outcome measures hemodynamic parameters including stroke volume, cardiac output, and cardiac index using electrical cardiometry (ICON CARDIOTRONIC, OSYPKA MEDICAL). Secondary outcomes include respiratory mechanics (atelectasis, plateau pressure, peak inspiratory pressure, dynamic compliance) and inflammatory markers (CRP, WBCs). Lung ultrasonography will assess atelectasis development. The trial is listed as not yet recruiting as of the registration date.
“The primary outcome is to compare the hemodynamic outcomes ( e.g SV , CO and CI ) using The ICON of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated trendelenburg position.”
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What changed
This entry registers a new clinical trial on ClinicalTrials.gov (NCT07550738) titled 'Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenburg Position.' The trial will enroll patients undergoing laparoscopic abdominal cancer surgeries and compare two ventilation strategies (PCV-VG vs VCV), measuring hemodynamic outcomes via electrical cardiometry and respiratory outcomes via lung ultrasonography.
Affected parties include anesthesiology and surgical departments planning trials involving mechanical ventilation optimization in laparoscopy. The registration provides public access to the trial's endpoints, interventions, and status, supporting transparency in clinical research. No compliance obligations are created by this registration entry.
Archived snapshot
Apr 25, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes e.g ( SV, CO ) and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenberg Postion
N/A NCT07550738 Kind: NA Apr 24, 2026
Abstract
The primary outcome is to compare the hemodynamic outcomes ( e.g SV , CO and CI ) using The ICON of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated trendelenburg position.
And the secondary outcomes is to compare the respiratory effects ( e.g atelectasis development , plateau pressure(Pplat) , peak inspiratory pressure(PIP) , dyn. compliance and postoperative inflammatory indicators e.g CRP and WBCs ) of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated trendelenburg position.
Conditions: PCV-VG Versus VCV Ventilation Mode Effects on Hemodynamics
Interventions: electrical cardiometry ('ICON CARDIOTRONIC, OSYPKA MEDICAL') , Lung ultrasonography (LUS) for atelectasis
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