PATH Spiritual Intervention for Cancer Distress
Summary
This clinical trial evaluates a spiritual health intervention called Personal Archetypes Toward Healing Trial (PATH) for cancer patients experiencing spiritual, religious, and existential distress. The PATH intervention draws on role-playing, archetype psychology, cognitive theory, emotion regulation therapy, and dignity therapy to address intrapersonal meaning, interpersonal faith distress, and transpersonal distress. Eligible participants have hematopoietic and lymphatic system neoplasms or malignant solid neoplasms; interventions include spiritual therapy, survey administration, and interview components.
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What changed
ClinicalTrials.gov registration for NCT07545291, a feasibility and effectiveness study of a spiritual health intervention (PATH) for improving spiritual, religious and existential distress in cancer patients. The trial covers topics including intrapersonal meaning and worth, intrapersonal and interpersonal distress related to faith, and transpersonal distress. Participants have hematopoietic and lymphatic system neoplasms or malignant solid neoplasms.
Affected parties include oncology researchers, clinical investigators, and healthcare providers involved in supportive cancer care. The registration signals an active research effort in spiritual care—a domain often overlooked in standard oncology practice—and may be relevant to institutional review boards, integrative medicine programs, and palliative care teams seeking evidence on spiritual interventions for distressed cancer patients.
Archived snapshot
Apr 22, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
A Spiritual Health Intervention (PATH) for Improving Spiritual, Religious and Emotional Distress in Cancer Patients
N/A NCT07545291 Kind: NA Apr 22, 2026
Abstract
This clinical trial tests the feasibility and effectiveness of a spiritual health intervention (Personal Archetypes Toward Healing Trial [PATH]) for improving spiritual, religious and existential distress in patients with cancer. Many patients with cancer find their diagnosis to elicit challenges to their sense of connection, meaning, and purpose. This distress can significantly impact their quality of life. However, spiritual care interventions are often overlooked. PATH builds on multiple theories and therapeutic practices such as role-playing, archetype psychology, cognitive theory, emotion regulation therapy, and dignity therapy. PATH sessions cover topics such as individuation, intrapersonal meaning and worth, intrapersonal distress and faith, interpersonal distress and faith, and transpersonal distress and faith. The PATH intervention may help cancer patients shift their perspectives and access new insights for working through their spiritual, religious and existential distress.
Conditions: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions: Spiritual Therapy, Survey Administration, Interview
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