HIIT Versus Moderate Continuous Training in ACHD
Summary
A single-center randomized controlled trial registered on ClinicalTrials.gov (NCT07546227) will evaluate the effect of interval training versus moderate continuous exercise training compared to usual care (no training) on exercise capacity in patients with adult congenital heart disease (CHD). The primary endpoint is peak VO2; secondary aims include assessing safety of exercise training in CHD, evaluating effects on cardiac structure and function, and measuring quality of life and long-term physical activity. Participants receive an exercise intervention (interval training or moderate continuous training) or no exercise control.
“This study is a single center randomized controlled trial evaluating the effect of an exercise training intervention (interval training or moderate continuous training) compared to usual care (no training) on exercise capacity in patients with congenital heart disease (CHD).”
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GovPing monitors ClinicalTrials.gov Studies for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 627 changes logged to date.
What changed
This document registers a new clinical trial (NCT07546227) on ClinicalTrials.gov, establishing the study parameters for a single-center randomized controlled trial in adults with congenital heart disease. The trial will randomize participants to interval training, moderate continuous training, or a control group receiving usual care with no exercise intervention. For healthcare providers and clinical investigators, this registry entry establishes the study's existence and scope, including primary and secondary endpoints, intervention types, and anticipated enrollment population. The study is registered with an anticipated start date and represents a formal clinical research protocol rather than a binding regulatory requirement.
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Apr 22, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
HIIT Vereus Moderate Continuous Training in ACHD
N/A NCT07546227 Kind: NA Apr 22, 2026
Abstract
This study is a single center randomized controlled trial evaluating the effect of an exercise training intervention (interval training or moderate continuous training) compared to usual care (no training) on exercise capacity in patients with congenital heart disease (CHD).
Our primary aim is to determine the impact of interval training (IT) compared to moderate continuous exercise training (MCT) versus controls (no exercise) on exercise capacity as measured by peak VO2. Secondary aims are to: 1) assess the safety of exercise training in CHD, 2) evaluate the effect of exercise training on cardiac structure and function and 3) assess the effects of exercise training on quality of life and long-term physical activity.
Conditions: Adult Congenital Heart Disease
Interventions: Exercise Intervention
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