USPTO Patent Application: Thiazolidine Linkers for Protein-Drug Conjugates
Summary
The USPTO has published a new patent application (US20260083856A1) detailing thiazolidine linkers for protein-drug conjugates and their uses in treating diseases. The application was filed on September 11, 2025, and is scheduled for publication on March 26, 2026.
What changed
This document is a publication of a United States patent application, specifically US20260083856A1, filed on September 11, 2025. The application describes novel thiazolidine (Tz) linkers designed for creating protein-drug conjugates, along with methods for their production and their application in treating diseases or disorders.
As this is a patent application, it does not impose immediate regulatory obligations on companies. However, it signals potential future intellectual property developments in the field of protein-drug conjugates. Companies involved in drug development, particularly those working with antibody-drug conjugates or similar targeted therapies, should monitor this application and related patents for potential licensing opportunities or competitive landscape shifts.
Archived snapshot
Mar 26, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
THIAZOLIDINE LINKERS FOR PROTEIN-DRUG CONJUGATES AND USES THEREOF
Application US20260083856A1 Kind: A1 Mar 26, 2026
Inventors
Xiao Cai, Stepan Chuprakov, Reji Nair, Ayodele Ogunkoya, Matthew Smith
Abstract
The present disclosure provides thiazolidine (Tz) linkers for protein-drug conjugates. In addition, the disclosure also encompasses compounds useful for producing such protein-drug conjugates, as well as methods for production of such protein-drug conjugates. The disclosure also encompasses methods of using the protein-drug conjugates for the treatment of a disease or disorder in a subject.
CPC Classifications
A61K 47/6851 A61K 47/6803 A61K 47/6889 C07K 16/32 C07K 2317/40 C07K 2317/94
Filing Date
2025-09-11
Application No.
19325974
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Source
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