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THIAZOLIDINE LINKERS FOR PROTEIN-DRUG CONJUGATES AND USES THEREOF

Application US20260083856A1 Kind: A1 Mar 26, 2026

Inventors

Xiao Cai, Stepan Chuprakov, Reji Nair, Ayodele Ogunkoya, Matthew Smith

Abstract

The present disclosure provides thiazolidine (Tz) linkers for protein-drug conjugates. In addition, the disclosure also encompasses compounds useful for producing such protein-drug conjugates, as well as methods for production of such protein-drug conjugates. The disclosure also encompasses methods of using the protein-drug conjugates for the treatment of a disease or disorder in a subject.

CPC Classifications

A61K 47/6851 A61K 47/6803 A61K 47/6889 C07K 16/32 C07K 2317/40 C07K 2317/94

Filing Date

2025-09-11

Application No.

19325974