Patent Application for cDNA Synthesis and Transcriptome Profiling
Summary
The USPTO has published a patent application (US20260085309A1) for compositions and methods related to cDNA synthesis and transcriptome profiling. The application details optimized template switching oligonucleotides designed to improve reverse transcription specificity and prevent concatemer formation. This is a new patent application filing, not a final rule or guidance.
What changed
The United States Patent and Trademark Office (USPTO) has published a new patent application, US20260085309A1, filed on September 14, 2023. The application, titled 'Compositions for cDNA Synthesis and Transcriptome Profiling and Methods of Use Thereof,' describes optimized template switching oligonucleotides with modifications to enhance the specificity of reverse transcription and prevent concatemer formation. The inventors listed are Anna Marie Pyle and Li-Tao Guo.
This publication represents a new patent application filing and does not impose any immediate regulatory obligations or compliance deadlines on regulated entities. Companies involved in biotechnology, pharmaceutical research, or molecular diagnostics may find the disclosed technology relevant to their research and development efforts. Compliance officers should note this as a potential future intellectual property development in the biotech sector.
Archived snapshot
Mar 27, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Compositions for cDNA Synthesis and Transcriptome Profiling and Methods of Use Thereof
Application US20260085309A1 Kind: A1 Mar 26, 2026
Inventors
Anna Marie Pyle, Li-Tao Guo
Abstract
The present invention provides optimized template switching oligonucleotides, methods, and kits for performing reverse transcription. The optimized template switching oligonucleotides include modifications of 5′ and 3′ ends to prevent the formation of concatemers and to enhance the specificity of reverse transcription.
CPC Classifications
C12N 15/1096 C12N 9/1276 C12P 19/34 C12Q 1/6848 C12Y 207/07049
Filing Date
2023-09-14
Application No.
19111674
Named provisions
Related changes
Get daily alerts for USPTO Patent Applications - Biotech (C12N)
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from USPTO.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when USPTO Patent Applications - Biotech (C12N) publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.