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Patent Application: Anti-FGFR2 Antibodies with Chemotherapy for Cancer Treatment

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Summary

The USPTO has published patent application US20260085123A1, filed by Five Prime Therapeutics, Inc. The application details the use of anti-FGFR2 antibodies in combination with mFOLFOX6 chemotherapy for treating certain cancers.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

This document is a published patent application (US20260085123A1) from the USPTO, filed by Five Prime Therapeutics, Inc. It describes novel uses of antibodies targeting fibroblast growth factor receptor 2 (FGFR2), specifically the FGFR2-IIIb isoform, in conjunction with mFOLFOX6 chemotherapy for the treatment of certain types of cancer.

As this is a patent application, it does not impose direct regulatory obligations on companies. However, it signifies potential future intellectual property claims and may influence research and development strategies in the oncology sector. Companies operating in drug development and cancer treatment should be aware of this filing for competitive intelligence and potential licensing considerations.

Archived snapshot

Mar 26, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

ANTI-FGFR2 ANTIBODIES IN COMBINATION WITH CHEMOTHERAPY AGENTS IN CANCER TREATMENT

Application US20260085123A1 Kind: A1 Mar 26, 2026

Assignee

FIVE PRIME THERAPEUTICS, INC.

Inventors

Helen L. COLLINS, James HNATYSZYN, Hong XIANG, Xiang ZHANG

Abstract

This application relates to uses of antibodies against fibroblast growth factor receptor 2 (FGFR2), including antibodies against the FGFR2 isoform FGFR2-IIIb (also known as FGFR2b), in treatment of certain cancers in combinations with mFOLFOX6 chemotherapy.

CPC Classifications

C07K 16/2863 A61K 9/0019 A61K 31/282 A61K 31/513 A61K 31/519 A61K 39/00 A61K 39/3955 A61P 35/00 A61P 35/04 A61K 2039/505 A61K 2039/545 C07K 2317/41 C07K 2317/732 C07K 2317/74 C07K 2317/76 C07K 2317/92

Filing Date

2025-05-05

Application No.

19199126

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Named provisions

Assignee Inventors Abstract CPC Classifications

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Last updated

Classification

Agency
USPTO
Published
March 26th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260085123A1

Who this affects

Applies to
Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Cancer Treatment
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Cancer Treatment Drug Development

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